Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 1393497..1394065 Replicon chromosome
Accession NZ_CP042862
Organism Serinicoccus profundi strain CGMCC 4.5582

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FA582_RS06340 Protein ID WP_010146998.1
Coordinates 1393739..1394065 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FA582_RS06335 Protein ID WP_029540555.1
Coordinates 1393497..1393736 (+) Length 80 a.a.

Genomic Context

FA582_RS06325FA582_RS06335FA582_RS06340FA582_RS06345FA582_RS06350FA582_RS16735FA582_RS06360FA582_RS06365FA582_RS06370FA582_RS06375FA582_RS06320FA582_RS06330
Location: 1389436..1389873 (438 bp)
Type: Others
Protein ID: WP_010147001.1
Location: 1393497..1393736 (240 bp)
Type: Antitoxin
Protein ID: WP_029540555.1
Location: 1393739..1394065 (327 bp)
Type: Toxin
Protein ID: WP_010146998.1
Location: 1394191..1394382 (192 bp)
Type: Others
Protein ID: WP_141567532.1
Location: 1394731..1395159 (429 bp)
Type: Others
Protein ID: WP_141567531.1
Location: 1395192..1396151 (960 bp)
Type: Others
Protein ID: WP_010146995.1
Location: 1396551..1396817 (267 bp)
Type: Others
Protein ID: WP_029540553.1
Location: 1396814..1397212 (399 bp)
Type: Others
Protein ID: WP_010146993.1
Location: 1397637..1397999 (363 bp)
Type: Others
Protein ID: WP_158640860.1
Location: 1398047..1398952 (906 bp)
Type: Others
Protein ID: WP_029540549.1
Location: 1388910..1389233 (324 bp)
Type: Others
Protein ID: WP_010147002.1
Location: 1389925..1393362 (3438 bp)
Type: Others
Protein ID: WP_010147000.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FA582_RS063201388910..1389233-324WP_010147002.1hypothetical protein-
FA582_RS063251389436..1389873+438WP_010147001.1hypothetical protein-
FA582_RS063301389925..1393362-3438WP_010147000.1SWIM zinc finger family protein-
FA582_RS063351393497..1393736+240WP_029540555.1DUF2191 domain-containing proteinAntitoxin
FA582_RS063401393739..1394065+327WP_010146998.1type II toxin-antitoxin system PemK/MazF family toxinToxin
FA582_RS063451394191..1394382+192WP_141567532.1hypothetical protein-
FA582_RS063501394731..1395159+429WP_141567531.1hypothetical protein-
FA582_RS167351395192..1396151+960WP_010146995.1HNH endonuclease-
FA582_RS063601396551..1396817+267WP_029540553.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
FA582_RS063651396814..1397212+399WP_010146993.1PIN domain-containing protein-
FA582_RS063701397637..1397999+363WP_158640860.1hypothetical protein-
FA582_RS063751398047..1398952+906WP_029540549.1plasmid pRiA4b ORF-3 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-103)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11468.24 Da        Isoelectric Point: 6.9035

>T136287 WP_010146998.1 NZ_CP042862:1393739-1394065 [Serinicoccus profundi]
MELPTRGELWWADLDDAGARPVVVVGRDAAIAGRRRALVAPCSTVVRGLPSEVRLEPGEEPVHRPCAAQLDALTDLPISV
LTRRLGRLSDAAMRRVCAALGVAADCSS

Download         Length: 327 bp

>T136287 NZ_CP042862:1393739-1394065 [Serinicoccus profundi]
ATGGAGCTCCCGACCAGGGGTGAGCTGTGGTGGGCGGACCTCGACGACGCCGGCGCCAGGCCCGTGGTGGTCGTCGGCCG
GGACGCCGCGATCGCCGGCCGTCGGCGCGCCCTCGTGGCGCCCTGCAGCACGGTCGTCCGGGGGCTGCCGAGCGAGGTGC
GGCTGGAGCCGGGTGAGGAACCGGTCCATCGTCCCTGCGCAGCACAGCTCGACGCCCTGACGGATCTGCCGATCTCGGTG
CTGACCCGCCGGCTCGGGCGCCTGAGCGACGCAGCGATGCGGCGGGTGTGCGCCGCGCTCGGCGTCGCCGCCGACTGCTC
CTCCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8697.68 Da        Isoelectric Point: 4.8430

>AT136287 WP_029540555.1 NZ_CP042862:1393497-1393736 [Serinicoccus profundi]
MARVRVSTTVDAELLACARKAHAGRTDASLVEEALEALLRNHRAAEVDEAYARAYRESPVEAPDEWGDLTTFLDAAARR

Download         Length: 240 bp

>AT136287 NZ_CP042862:1393497-1393736 [Serinicoccus profundi]
ATGGCCAGGGTGAGAGTGAGTACGACGGTGGATGCAGAGTTGCTGGCGTGCGCGCGGAAGGCGCATGCGGGCAGGACGGA
TGCGTCCCTGGTGGAGGAGGCGCTGGAGGCGCTGCTGCGGAACCACCGGGCGGCCGAGGTCGACGAGGCCTACGCCCGGG
CCTACCGCGAGAGCCCGGTGGAGGCGCCCGACGAGTGGGGGGACCTGACGACCTTCCTCGACGCGGCCGCGAGGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References