Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4512920..4513466 Replicon chromosome
Accession NZ_CP042860
Organism Providencia sp. 1701091

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FVA70_RS21000 Protein ID WP_109912959.1
Coordinates 4513185..4513466 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FVA70_RS20995 Protein ID WP_102140619.1
Coordinates 4512920..4513204 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVA70_RS20970 4507995..4508972 - 978 WP_004265237.1 6-phosphofructokinase -
FVA70_RS20975 4509378..4510322 - 945 WP_109912960.1 phosphatidate cytidylyltransferase -
FVA70_RS20980 4510319..4510960 - 642 WP_110731554.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
FVA70_RS20985 4511198..4511950 - 753 WP_164529272.1 M48 family metallopeptidase -
FVA70_RS20990 4512177..4512758 - 582 WP_117162998.1 HutD family protein -
FVA70_RS20995 4512920..4513204 + 285 WP_102140619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FVA70_RS21000 4513185..4513466 + 282 WP_109912959.1 type II toxin-antitoxin system YafQ family toxin Toxin
FVA70_RS21005 4513761..4514348 - 588 WP_164529273.1 Spy/CpxP family protein refolding chaperone -
FVA70_RS21010 4514499..4515197 + 699 WP_004907000.1 envelope stress response regulator transcription factor CpxR -
FVA70_RS21015 4515194..4516564 + 1371 WP_004906999.1 envelope stress sensor histidine kinase CpxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10968.80 Da        Isoelectric Point: 9.1315

>T136276 WP_109912959.1 NZ_CP042860:4513185-4513466 [Providencia sp. 1701091]
MLKIRVKSQFKKDLKKSLSDKKRNTQLLKELIDNHLCITGSVPAEYLPHPLKGNWRPCYEYHIQPDFLLIWDINYQTNEI
ILVRCGSHSELFG

Download         Length: 282 bp

>T136276 NZ_CP055306:c255787-255383 [Mannheimia pernigra]
ATGATCTATATGCTTGATACCAATATTTTGATTTATTTAATGAAAAATCGACCGCTTGCAGTGGCAGAACGTGTGGCACA
ACTTACGCCAAGTGATCAATTAGTTATGAGCTTTATTACCTATGCTGAATTGCTCAAAGGAGCAAATGGCAGTGCTAATC
CGGAAAAAGCCTTAGCGAATATCGAAAAGTTGAAACAACGTATTTCAGTTGTTTACCCAAATGAAAAAATCTGTGAATTT
TATGGTGTTTGGGCAAATAAATTGAAGTTACAAGGCAAGCCCATTGGTGGAAATGATTTATGGATTGCTTGTCACGCTTT
AGCTTGTAATGCGATATTAGTAACGCATAATGTCAAAGAGTCCGAGCGAATTGAAGCATTAAATTGGCAAGATTGGACGT
GTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10420.71 Da        Isoelectric Point: 4.6412

>AT136276 WP_102140619.1 NZ_CP042860:4512920-4513204 [Providencia sp. 1701091]
MASTQHKTDIVRARIEPKVRENAEAVLSELGISMSDAIRIFVKQISLRQAFPIELKTPNSITLEAINAPTTDETFDSAED
LFSQVSKSDAENSR

Download         Length: 285 bp

>AT136276 NZ_CP042860:4512920-4513204 [Providencia sp. 1701091]
ATGGCCAGTACTCAACATAAAACAGATATTGTCAGAGCCAGAATTGAGCCTAAAGTCAGGGAAAATGCTGAAGCAGTGTT
ATCTGAATTAGGGATTAGCATGTCTGATGCTATTCGTATTTTCGTCAAGCAAATATCATTGCGACAAGCTTTTCCTATTG
AGTTAAAAACACCAAACTCAATTACATTAGAAGCTATTAATGCACCAACTACAGACGAAACATTTGACTCTGCTGAAGAT
TTATTTAGCCAAGTGAGCAAGTCCGATGCTGAAAATTCGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References