Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4485139..4485685 Replicon chromosome
Accession NZ_CP042859
Organism Providencia sp. 1701011

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FVA69_RS20790 Protein ID WP_109912959.1
Coordinates 4485404..4485685 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FVA69_RS20785 Protein ID WP_102140619.1
Coordinates 4485139..4485423 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVA69_RS20760 4480214..4481191 - 978 WP_004265237.1 6-phosphofructokinase -
FVA69_RS20765 4481597..4482541 - 945 WP_109912960.1 phosphatidate cytidylyltransferase -
FVA69_RS20770 4482538..4483179 - 642 WP_110731554.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
FVA69_RS20775 4483417..4484169 - 753 WP_164529272.1 M48 family metallopeptidase -
FVA69_RS20780 4484396..4484977 - 582 WP_117162998.1 HutD family protein -
FVA69_RS20785 4485139..4485423 + 285 WP_102140619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FVA69_RS20790 4485404..4485685 + 282 WP_109912959.1 type II toxin-antitoxin system YafQ family toxin Toxin
FVA69_RS20795 4485980..4486567 - 588 WP_164529273.1 Spy/CpxP family protein refolding chaperone -
FVA69_RS20800 4486718..4487416 + 699 WP_004907000.1 envelope stress response regulator transcription factor CpxR -
FVA69_RS20805 4487413..4488783 + 1371 WP_004906999.1 envelope stress sensor histidine kinase CpxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10968.80 Da        Isoelectric Point: 9.1315

>T136272 WP_109912959.1 NZ_CP042859:4485404-4485685 [Providencia sp. 1701011]
MLKIRVKSQFKKDLKKSLSDKKRNTQLLKELIDNHLCITGSVPAEYLPHPLKGNWRPCYEYHIQPDFLLIWDINYQTNEI
ILVRCGSHSELFG

Download         Length: 282 bp

>T136272 NZ_CP042859:4485404-4485685 [Providencia sp. 1701011]
ATGCTGAAAATTCGCGTTAAATCCCAATTCAAAAAAGACTTAAAAAAGTCGTTATCTGACAAAAAAAGAAATACTCAGCT
ATTAAAAGAGTTAATCGATAACCACCTATGCATTACTGGCTCTGTTCCAGCAGAATATTTGCCTCATCCCTTAAAAGGAA
ACTGGAGACCTTGCTATGAATATCACATACAACCCGATTTTTTATTAATTTGGGATATAAACTACCAAACCAATGAAATC
ATATTAGTTCGCTGTGGTTCTCATTCTGAATTATTTGGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10420.71 Da        Isoelectric Point: 4.6412

>AT136272 WP_102140619.1 NZ_CP042859:4485139-4485423 [Providencia sp. 1701011]
MASTQHKTDIVRARIEPKVRENAEAVLSELGISMSDAIRIFVKQISLRQAFPIELKTPNSITLEAINAPTTDETFDSAED
LFSQVSKSDAENSR

Download         Length: 285 bp

>AT136272 NZ_CP042859:4485139-4485423 [Providencia sp. 1701011]
ATGGCCAGTACTCAACATAAAACAGATATTGTCAGAGCCAGAATTGAGCCTAAAGTCAGGGAAAATGCTGAAGCAGTGTT
ATCTGAATTAGGGATTAGCATGTCTGATGCTATTCGTATTTTCGTCAAGCAAATATCATTGCGACAAGCTTTTCCTATTG
AGTTAAAAACACCAAACTCAATTACATTAGAAGCTATTAATGCACCAACTACAGACGAAACATTTGACTCTGCTGAAGAT
TTATTTAGCCAAGTGAGCAAGTCCGATGCTGAAAATTCGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References