Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2622561..2622832 Replicon chromosome
Accession NZ_CP042846
Organism Escherichia coli strain JME64

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2622599..2622702 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2622561..2622832 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVE20_RS12825 2619718..2621157 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FVE20_RS12830 2621275..2621511 + 237 WP_001295499.1 DUF1480 family protein -
FVE20_RS12835 2621616..2621807 + 192 WP_000457842.1 YebW family protein -
FVE20_RS12840 2621808..2622464 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2622561..2622832 + 272 - - Antitoxin
- 2622599..2622702 - 104 - - Toxin
FVE20_RS12845 2622860..2623201 - 342 WP_000976476.1 YebY family protein -
FVE20_RS12850 2623214..2624086 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FVE20_RS12855 2624090..2624464 - 375 WP_000168747.1 CopC domain-containing protein YobA -
FVE20_RS12860 2624603..2624833 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FVE20_RS12865 2624935..2625591 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FVE20_RS12870 2625615..2626277 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T136221 NZ_CP042846:c2622702-2622599 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT136221 NZ_CP042846:2622561-2622832 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References