Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2627674..2627945 Replicon chromosome
Accession NZ_CP042844
Organism Escherichia coli strain JME66

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2627712..2627815 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2627674..2627945 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVE22_RS12855 2624831..2626270 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FVE22_RS12860 2626388..2626624 + 237 WP_001295499.1 DUF1480 family protein -
FVE22_RS12865 2626729..2626920 + 192 WP_000457842.1 YebW family protein -
FVE22_RS12870 2626921..2627577 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2627674..2627945 + 272 - - Antitoxin
- 2627712..2627815 - 104 - - Toxin
FVE22_RS12875 2627973..2628314 - 342 WP_000976476.1 YebY family protein -
FVE22_RS12880 2628327..2629199 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
FVE22_RS12885 2629203..2629577 - 375 WP_000168747.1 CopC domain-containing protein YobA -
FVE22_RS12890 2629716..2629946 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FVE22_RS12895 2630048..2630704 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
FVE22_RS12900 2630728..2631390 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T136135 NZ_CP042844:c2627815-2627712 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT136135 NZ_CP042844:2627674-2627945 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References