Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ImmA-IrrE/-
Location 1818482..1819182 Replicon chromosome
Accession NZ_CP042839
Organism Enterococcus sp. DA9

Toxin (Protein)


Gene name IrrE Uniprot ID -
Locus tag FTX43_RS09685 Protein ID WP_002290432.1
Coordinates 1818482..1818907 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name ImmA Uniprot ID -
Locus tag FTX43_RS09690 Protein ID WP_002313665.1
Coordinates 1818925..1819182 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTX43_RS09660 1814537..1815298 + 762 WP_002320129.1 DUF3427 domain-containing protein -
FTX43_RS09665 1815431..1816887 + 1457 Protein_1709 FRG domain-containing protein -
FTX43_RS09675 1817492..1818250 + 759 WP_002342169.1 restriction endonuclease -
FTX43_RS09685 1818482..1818907 - 426 WP_002290432.1 hypothetical protein Toxin
FTX43_RS09690 1818925..1819182 - 258 WP_002313665.1 hypothetical protein Antitoxin
FTX43_RS14940 1819384..1819686 + 303 Protein_1713 hypothetical protein -
FTX43_RS14945 1819702..1820038 + 337 Protein_1714 hypothetical protein -
FTX43_RS09705 1820513..1820743 + 231 WP_002320124.1 hypothetical protein -
FTX43_RS09710 1820740..1821006 + 267 WP_002292138.1 type II toxin-antitoxin system RelE/ParE family toxin -
FTX43_RS09715 1821258..1821485 + 228 WP_002313668.1 hypothetical protein -
FTX43_RS09720 1821501..1822667 + 1167 WP_002313669.1 oxygen-independent coproporphyrinogen III oxidase -
FTX43_RS09725 1822901..1823944 + 1044 WP_002292136.1 heat-inducible transcriptional repressor HrcA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16691.78 Da        Isoelectric Point: 4.6731

>T136062 WP_002290432.1 NZ_CP042839:c1818907-1818482 [Enterococcus sp. DA9]
MNVVSEGLYFEAADLANELSEEVSYYCSKKMEHVKCYDIENYVNEVEDVEFIDYDFKDNLSKKMLGSITKVHGEIIITTN
QHLMLERKNFTKMHEIIHYYKDVPYLGESHAFSDMILEDTYLPEDYKKTSSKYRCQYPHGE

Download         Length: 426 bp

>T136062 NZ_CP042839:c1818907-1818482 [Enterococcus sp. DA9]
TTGAATGTGGTTTCTGAAGGACTTTATTTTGAAGCTGCAGACCTTGCAAATGAACTCTCAGAAGAAGTTAGTTATTACTG
TTCAAAGAAAATGGAACATGTAAAATGCTACGACATTGAGAATTATGTGAATGAAGTAGAAGATGTAGAATTCATCGATT
ACGACTTCAAAGATAACTTAAGTAAGAAAATGCTTGGTTCCATTACAAAAGTTCATGGCGAAATCATCATTACCACCAAT
CAACATTTAATGCTTGAACGCAAAAATTTTACAAAAATGCATGAGATCATCCATTATTATAAGGACGTCCCCTATCTTGG
AGAATCTCATGCATTTTCTGATATGATTTTAGAAGATACTTATTTGCCAGAAGACTATAAAAAAACTTCGAGCAAATATA
GGTGCCAGTATCCTCATGGCGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9913.09 Da        Isoelectric Point: 4.2290

>AT136062 WP_002313665.1 NZ_CP042839:c1819182-1818925 [Enterococcus sp. DA9]
MLSNYQLVTVIADFFNVSTDFLLNRTSDPTPPKRSEEDQLGDSILSHFRLNTADMEVEDIEELEEELNEYMDFLVQRAKA
KKNKK

Download         Length: 258 bp

>AT136062 NZ_CP042839:c1819182-1818925 [Enterococcus sp. DA9]
TTGTTGTCAAATTATCAGCTAGTCACAGTAATAGCAGATTTCTTCAATGTTTCTACAGATTTTCTACTAAATAGAACCTC
TGATCCGACTCCTCCAAAACGTAGCGAAGAAGATCAGCTTGGAGACAGTATTCTTTCTCACTTCAGATTGAATACTGCAG
ATATGGAAGTAGAAGACATTGAAGAATTGGAAGAAGAATTAAATGAATATATGGACTTTTTAGTTCAACGTGCAAAAGCA
AAGAAAAATAAAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References