Detailed information of TA system TA136053

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 4418536..4419041
• Replicon: chromosome
• Accession: NZ_CP042826
• Organism: Rhizobium sp. WL3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FVA81_RS24745
• Protein ID: WP_147888632.1
• Coordinates: 4418536..4418790 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FVA81_RS24750
• Protein ID: WP_147888633.1
• Coordinates: 4418787..4419041 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FVA81_RS24725	4414103..4415023	+	921	WP_147888628.1	hypothetical protein	-
FVA81_RS24730	4415034..4416458	-	1425	WP_147888629.1	3-mercaptopyruvate sulfurtransferase	-
FVA81_RS24735	4416487..4417218	-	732	WP_147888630.1	alanyl-tRNA editing protein	-
FVA81_RS24740	4417238..4418275	-	1038	WP_147888631.1	cysteine synthase A	-
FVA81_RS24745	4418536..4418790	-	255	WP_147888632.1	Txe/YoeB family addiction module toxin	Toxin
FVA81_RS24750	4418787..4419041	-	255	WP_147888633.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FVA81_RS24755	4419596..4421044	-	1449	WP_147888634.1	DNA photolyase family protein	-
FVA81_RS24760	4421146..4421373	-	228	WP_147888635.1	hypothetical protein	-
FVA81_RS24770	4421801..4422082	+	282	WP_147888636.1	hypothetical protein	-
FVA81_RS24775	4422234..4422488	+	255	WP_147888637.1	hypothetical protein	-
FVA81_RS24785	4422914..4423585	+	672	WP_147888638.1	protein-L-isoaspartate O-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10118.59 Da
• Isoelectric Point: 10.1847

>T136053 WP_147888632.1 NZ_CP042826:c4418790-4418536 [Rhizobium sp. WL3]
VKLIFHARAWEDYLYWQSTDAKMLARVNQLIKETSRSPFQGIGKPEPLRGELRGWWSRRINQEHRLVYRPTEDGILIAQC
RHHY

Nucleotide

• Length: 255 bp

>T136053 NZ_CP042826:c4418790-4418536 [Rhizobium sp. WL3]
GTGAAGCTGATCTTCCACGCGCGTGCCTGGGAGGACTACCTGTATTGGCAGTCCACGGATGCAAAAATGCTGGCACGCGT
CAATCAGCTGATCAAGGAAACCAGCCGGTCACCGTTTCAGGGCATTGGCAAACCGGAGCCGCTGCGGGGCGAGTTGCGCG
GCTGGTGGTCGCGGCGCATCAACCAGGAACATCGGCTCGTTTATCGCCCAACGGAAGACGGCATCCTGATCGCGCAGTGC
CGCCATCATTATTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9532.68 Da
• Isoelectric Point: 4.5386

>AT136053 WP_147888633.1 NZ_CP042826:c4419041-4418787 [Rhizobium sp. WL3]
MRTTSYSDLRKNLASLLDSVTEDRTPVLITRDRGKPAAVLMSVEDFASYEETQYLLKSPRNAERLLEAVRDLDDGKGEVR
ELSE

Nucleotide

• Length: 255 bp

>AT136053 NZ_CP042826:c4419041-4418787 [Rhizobium sp. WL3]
ATGAGAACCACATCCTACAGCGACCTGCGTAAGAACCTCGCCTCACTGCTCGATAGTGTGACGGAGGACCGCACTCCTGT
CCTGATCACCCGTGATCGCGGCAAACCAGCCGCCGTTCTGATGTCGGTGGAGGATTTCGCGTCCTATGAGGAAACGCAGT
ATCTCTTGAAGAGCCCCCGCAACGCCGAACGCCTGCTCGAAGCGGTGCGTGACCTCGATGACGGCAAGGGCGAAGTGCGT
GAGCTTTCGGAGTGA