Detailed information of TA system TA136052

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 3815061..3815614
• Replicon: chromosome
• Accession: NZ_CP042826
• Organism: Rhizobium sp. WL3

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: FVA81_RS21610
• Protein ID: WP_147888175.1
• Coordinates: 3815366..3815614 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FVA81_RS21605
• Protein ID: WP_147888174.1
• Coordinates: 3815061..3815369 (-)
• Length: 103 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FVA81_RS21575	3810449..3810658	-	210	WP_006727165.1	cold-shock protein	-
FVA81_RS21580	3811118..3811609	+	492	WP_147888169.1	histidine kinase	-
FVA81_RS21585	3811946..3812995	+	1050	WP_147888170.1	fatty acid desaturase	-
FVA81_RS21590	3813084..3813776	-	693	WP_147888171.1	YafY family transcriptional regulator	-
FVA81_RS21595	3813901..3814536	+	636	WP_147888172.1	LysE family translocator	-
FVA81_RS21600	3814540..3815007	-	468	WP_147888173.1	GNAT family N-acetyltransferase	-
FVA81_RS21605	3815061..3815369	-	309	WP_147888174.1	BrnA antitoxin family protein	Antitoxin
FVA81_RS21610	3815366..3815614	-	249	WP_147888175.1	BrnT family toxin	Toxin
FVA81_RS21615	3815674..3815994	-	321	WP_147888176.1	YnfA family protein	-
FVA81_RS21620	3816044..3816862	-	819	WP_147888177.1	EAL domain-containing protein	-
FVA81_RS21625	3817056..3818312	-	1257	WP_147888178.1	SH3 domain-containing protein	-
FVA81_RS21630	3818335..3819357	-	1023	WP_147888179.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-77)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (27-100)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 9267.74 Da
• Isoelectric Point: 11.2212

>T136052 WP_147888175.1 NZ_CP042826:c3815614-3815366 [Rhizobium sp. WL3]
MIIVWDEPKRLANIDKHGLDFADLSLEFFQRAHIRPANRGRLQAIGRLEDGTIAVIFVRLGTEGLSVISMRSANPAERRA
LR

Nucleotide

• Length: 249 bp

>T136052 NZ_CP042826:c3815614-3815366 [Rhizobium sp. WL3]
ATGATCATCGTCTGGGATGAACCGAAACGGCTCGCGAATATCGACAAGCATGGTCTGGATTTCGCCGACCTGTCGCTCGA
GTTTTTCCAGCGCGCTCACATCCGCCCGGCGAACCGAGGCCGACTGCAGGCGATCGGACGGCTTGAGGACGGCACAATCG
CCGTAATTTTCGTCCGACTCGGCACGGAGGGTCTCTCGGTGATCTCAATGCGGTCAGCAAATCCGGCCGAAAGGAGGGCG
TTGCGATGA

Antitoxin

Protein

• Length: 103 a.a.
• Molecular weight: 11678.16 Da
• Isoelectric Point: 5.3030

>AT136052 WP_147888174.1 NZ_CP042826:c3815369-3815061 [Rhizobium sp. WL3]
MKKTKPVSDDFREGRGYTRADWDEVDDNPEMTEAEIAELRPFREVFPDLAASIDRKLGRPKAENPKKAISLRLDQDVIDR
FKATGDGWQSRMNEALRKAVGL

Nucleotide

• Length: 309 bp

>AT136052 NZ_CP042826:c3815369-3815061 [Rhizobium sp. WL3]
ATGAAGAAGACCAAGCCTGTGTCAGACGATTTTCGCGAAGGCCGCGGCTATACCCGCGCCGATTGGGACGAAGTTGATGA
CAATCCCGAGATGACCGAGGCCGAGATCGCAGAACTGCGGCCCTTCCGCGAGGTGTTTCCCGACCTTGCTGCTTCAATCG
ACCGCAAGCTCGGGCGGCCCAAGGCCGAGAACCCCAAAAAAGCGATCAGCCTCCGGCTCGACCAGGATGTGATCGACCGA
TTCAAGGCGACAGGAGACGGCTGGCAGTCGCGGATGAACGAGGCTTTGCGCAAGGCGGTGGGGCTGTGA