Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 2938977..2939601 Replicon chromosome
Accession NZ_CP042826
Organism Rhizobium sp. WL3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FVA81_RS17370 Protein ID WP_147887517.1
Coordinates 2938977..2939381 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FVA81_RS17375 Protein ID WP_136556790.1
Coordinates 2939371..2939601 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVA81_RS17345 2935123..2936160 + 1038 WP_147887513.1 dihydroorotase -
FVA81_RS17350 2936258..2936803 - 546 WP_147887514.1 hypothetical protein -
FVA81_RS17355 2936937..2937092 - 156 WP_136556794.1 DUF3096 domain-containing protein -
FVA81_RS17360 2937222..2937914 + 693 WP_147887515.1 orotate phosphoribosyltransferase -
FVA81_RS17365 2937992..2938918 + 927 WP_147887516.1 carbohydrate kinase -
FVA81_RS17370 2938977..2939381 - 405 WP_147887517.1 PIN domain-containing protein Toxin
FVA81_RS17375 2939371..2939601 - 231 WP_136556790.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
FVA81_RS17380 2939710..2939857 + 148 Protein_2699 carbohydrate kinase -
FVA81_RS25735 2940100..2940474 + 375 WP_187182103.1 hypothetical protein -
FVA81_RS17390 2940547..2940630 - 84 Protein_2701 AbrB family transcriptional regulator -
FVA81_RS17395 2940731..2941285 - 555 WP_147887518.1 hypothetical protein -
FVA81_RS17400 2941447..2943075 - 1629 WP_147887519.1 glucose-6-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-111)

Antitoxin

SpoVT-AbrB domain

(5-33)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14618.91 Da        Isoelectric Point: 5.1238

>T136050 WP_147887517.1 NZ_CP042826:c2939381-2938977 [Rhizobium sp. WL3]
MGARFVDTNVLVYLASGDVQRADRAEAILAGGGTISVQVLNEIANVMRRKMRMSWPDTNVFLDTIRALLTVEPVTVATHE
QGLVVSERYGLSIYDAMIVSAALLAGCETLLSEAMQDGLIVDGRLRIINPFRHS

Download         Length: 405 bp

>T136050 NZ_CP042826:c2939381-2938977 [Rhizobium sp. WL3]
ATGGGCGCTAGGTTCGTCGATACGAACGTGCTGGTCTATCTCGCCTCCGGCGATGTCCAACGAGCGGATCGGGCGGAGGC
TATACTTGCCGGAGGCGGCACGATCAGCGTTCAAGTGCTCAACGAAATTGCCAATGTGATGCGTCGGAAAATGCGGATGT
CGTGGCCGGATACAAATGTATTTCTCGACACGATCCGGGCCCTGCTGACCGTGGAGCCGGTCACGGTGGCAACCCACGAG
CAGGGGCTCGTTGTCTCCGAGCGTTATGGGTTATCCATCTATGACGCGATGATTGTTTCAGCAGCACTCCTGGCCGGGTG
TGAAACGTTGCTGTCTGAAGCCATGCAGGACGGCCTCATCGTTGATGGCCGCTTACGCATCATAAATCCGTTCAGACATT
CGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8760.99 Da        Isoelectric Point: 8.8306

>AT136050 WP_136556790.1 NZ_CP042826:c2939601-2939371 [Rhizobium sp. WL3]
MQIAKWGNSLAVRLPASVVEALNLKEGDDIEIRAADWRELDVARKPTPEDLLRRLRSFRGRLPVDFKFDRDEANGR

Download         Length: 231 bp

>AT136050 NZ_CP042826:c2939601-2939371 [Rhizobium sp. WL3]
ATGCAGATCGCCAAATGGGGCAACAGCCTTGCGGTGCGCCTTCCCGCTAGTGTGGTCGAAGCGCTGAACCTGAAGGAAGG
CGACGACATCGAAATTCGCGCCGCCGACTGGCGCGAGCTCGATGTGGCGCGCAAGCCTACCCCGGAGGATCTTCTTCGGC
GGCTGCGGTCCTTCCGGGGACGGTTGCCGGTTGATTTCAAGTTTGACCGGGATGAGGCGAATGGGCGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References