Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE-PrpA/RHH(antitoxin)
Location 2184952..2185489 Replicon chromosome
Accession NZ_CP042826
Organism Rhizobium sp. WL3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FVA81_RS13760 Protein ID WP_210248027.1
Coordinates 2184952..2185242 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag FVA81_RS13765 Protein ID WP_147886968.1
Coordinates 2185244..2185489 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVA81_RS13745 2181829..2182257 + 429 WP_147888857.1 hypothetical protein -
FVA81_RS13750 2182374..2183564 + 1191 WP_147886965.1 multidrug effflux MFS transporter -
FVA81_RS13755 2183617..2184840 - 1224 WP_147886966.1 argininosuccinate synthase -
FVA81_RS13760 2184952..2185242 - 291 WP_210248027.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FVA81_RS13765 2185244..2185489 - 246 WP_147886968.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
FVA81_RS13770 2185590..2186453 + 864 WP_147886969.1 SDR family NAD(P)-dependent oxidoreductase -
FVA81_RS13775 2186528..2187169 + 642 WP_147886970.1 LysE family translocator -
FVA81_RS13780 2187202..2188428 - 1227 WP_187182404.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
FVA81_RS13785 2188678..2189181 - 504 WP_136560043.1 hypothetical protein -
FVA81_RS13790 2189446..2189826 - 381 WP_147886972.1 DUF1232 domain-containing protein -
FVA81_RS13795 2189903..2190205 - 303 WP_136559814.1 4a-hydroxytetrahydrobiopterin dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10994.61 Da        Isoelectric Point: 10.2760

>T136049 WP_210248027.1 NZ_CP042826:c2185242-2184952 [Rhizobium sp. WL3]
VATYKLSPLARKDLEGIWCYSWERWSKDQADRYYSQIVAALHGLANGSREGKPLIGFKTGYLSLSCGSHFISYARRKNAV
EVIRILHQRTNIGRHL

Download         Length: 291 bp

>T136049 NZ_CP042826:c2185242-2184952 [Rhizobium sp. WL3]
GTGGCGACCTACAAGCTCTCGCCGCTGGCGCGGAAAGATCTTGAAGGAATTTGGTGTTACTCATGGGAACGATGGTCTAA
GGACCAAGCCGATAGATATTATTCGCAAATCGTGGCTGCACTCCATGGCTTGGCGAACGGTAGCAGAGAGGGTAAACCGC
TCATTGGCTTCAAAACCGGATATCTCAGTCTATCTTGTGGGTCGCATTTCATAAGCTATGCTCGGCGTAAGAACGCCGTC
GAGGTCATCCGCATCCTTCACCAACGGACGAATATCGGCCGTCATCTCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8725.71 Da        Isoelectric Point: 3.8810

>AT136049 WP_147886968.1 NZ_CP042826:c2185489-2185244 [Rhizobium sp. WL3]
MNKVTTVTVSGELAEFMEAKISAGDYASEAEVIEAALALLRDEIDGLAAIRAAIEEGEASGEPQPFDPVQFLDEIHRKYG
E

Download         Length: 246 bp

>AT136049 NZ_CP055224:c4457373-4456957 [Pectobacterium atrosepticum]
ATGATGTATGCAGATGCCATCAAGGCAGCTAACGATCTGACGAGTATCGTACCGTTCCTCGGGGGCAGCACCTCTCGTAA
GGATTATGAGGATGCACTGAAACTCACTGAATATCTGATCGAGAGTGAGCCTGATAGTTCGCTAATCGATATGCTGACTG
CCAAAATTGATAAATACGAAAATGAGGCGCCGGAGTTTGCAGCCTTCAACGAACGTATTAAAGCACTCCCTGCCGGTATC
GCTTTGCTACGTGTCCTCATGGATCAGCACCAGCTAATGCAGAGTGATTTTGAAGCTGAGATCGGTAAAAAGTCTCTGGT
ATCCCGTATTCTAAACGGTGAGCGTACGTTAACACTTGCTCATATGAGAGCTCTCGCTAAGCGATTCAATATTCCCGTGA
GTGCTTTTGTTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References