Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 327705..328372 Replicon chromosome
Accession NZ_CP042823
Organism Methylobacterium sp. WL1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FVA80_RS01785 Protein ID WP_147906080.1
Coordinates 327959..328372 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FVA80_RS01780 Protein ID WP_147906081.1
Coordinates 327705..327962 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVA80_RS30270 322893..323039 + 147 WP_187193566.1 hypothetical protein -
FVA80_RS01765 323075..323551 - 477 WP_147906082.1 hypothetical protein -
FVA80_RS01770 323721..324971 - 1251 WP_147906156.1 phosphoglycerate dehydrogenase -
FVA80_RS01775 325773..327485 + 1713 WP_147853718.1 30S ribosomal protein S1 -
FVA80_RS01780 327705..327962 + 258 WP_147906081.1 plasmid stability protein stbC Antitoxin
FVA80_RS01785 327959..328372 + 414 WP_147906080.1 PIN domain-containing protein Toxin
FVA80_RS30275 328482..328649 + 168 WP_187193567.1 hypothetical protein -
FVA80_RS01790 328845..329807 + 963 WP_147906079.1 signal peptide peptidase SppA -
FVA80_RS01795 329867..330178 + 312 WP_091785957.1 integration host factor subunit beta -
FVA80_RS01800 330198..330569 + 372 WP_147906155.1 LapA family protein -
FVA80_RS01805 330580..331239 - 660 WP_187193568.1 phosphoribosylanthranilate isomerase -
FVA80_RS01810 331258..332367 - 1110 WP_147906078.1 DUF2125 domain-containing protein -
FVA80_RS01815 332520..332966 - 447 WP_147906077.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 14847.06 Da        Isoelectric Point: 8.4447

>T136042 WP_147906080.1 NZ_CP042823:327959-328372 [Methylobacterium sp. WL1]
MIVLDTNAIAEPWKSQPGPTVIAWTDAQMVEPLYPSTITVAEVRFGLATMPDGNRRRIYRERLEREVLPVFSGRILSFDL
AASQAYAALMARARAAGRGIGRADGYIAATAAAHEMTVAARYVGPFEAAGPTVINPW

Download         Length: 414 bp

>T136042 NZ_CP042823:327959-328372 [Methylobacterium sp. WL1]
ATGATCGTCCTCGATACCAATGCTATCGCGGAACCCTGGAAGTCCCAGCCGGGCCCCACGGTGATCGCCTGGACCGATGC
GCAGATGGTCGAGCCTCTCTACCCGTCCACGATCACCGTCGCTGAAGTGCGCTTCGGCCTGGCGACGATGCCGGACGGCA
ATCGGCGCCGGATTTATCGGGAGCGTCTGGAACGCGAGGTCCTGCCCGTCTTCTCGGGGCGGATCCTGTCCTTCGATCTG
GCCGCCTCCCAGGCGTACGCGGCCCTGATGGCGCGGGCGAGGGCGGCCGGCAGAGGCATCGGCCGGGCGGACGGCTACAT
CGCCGCCACGGCCGCCGCGCACGAAATGACGGTCGCCGCCCGCTACGTCGGTCCGTTCGAAGCGGCCGGCCCGACCGTCA
TCAATCCTTGGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9316.62 Da        Isoelectric Point: 6.7195

>AT136042 WP_147906081.1 NZ_CP042823:327705-327962 [Methylobacterium sp. WL1]
MPAITIHNVPDAEHRALRARAALRGRSTEAEIRSTPEQAAKPEGRLKLGSLLAFIARDAGGMTEAEAEHIEALCQRTPVE
PMRFE

Download         Length: 258 bp

>AT136042 NZ_CP042823:327705-327962 [Methylobacterium sp. WL1]
ATGCCGGCCATCACGATCCATAACGTTCCCGACGCGGAGCATCGCGCCCTGCGTGCGCGGGCCGCATTGCGCGGTCGCAG
CACCGAGGCTGAAATCCGCAGCACCCCCGAACAGGCCGCTAAGCCCGAGGGCCGCCTGAAGCTCGGATCGCTGCTGGCGT
TCATCGCGCGCGACGCCGGCGGGATGACCGAAGCCGAAGCGGAGCACATCGAGGCTTTGTGCCAACGGACACCGGTCGAG
CCGATGCGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References