Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 905916..906441 Replicon chromosome
Accession NZ_CP042812
Organism Malaciobacter canalis strain LMG 29148

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ACAN_RS04485 Protein ID WP_099333964.1
Coordinates 906157..906441 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ACAN_RS04480 Protein ID WP_099333963.1
Coordinates 905916..906173 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACAN_RS04460 901258..902115 + 858 WP_196778770.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
ACAN_RS04465 902112..903674 + 1563 WP_099333960.1 alginate lyase family protein -
ACAN_RS04470 903671..904834 + 1164 WP_099333961.1 glycosyltransferase family 4 protein -
ACAN_RS04475 904831..905781 + 951 WP_099333962.1 NAD-dependent epimerase/dehydratase family protein -
ACAN_RS04480 905916..906173 + 258 WP_099333963.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ACAN_RS04485 906157..906441 + 285 WP_099333964.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACAN_RS04490 906748..907005 + 258 WP_099333965.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
ACAN_RS04495 906996..907250 + 255 WP_099333966.1 Txe/YoeB family addiction module toxin -
ACAN_RS04500 907250..908212 + 963 WP_099333967.1 glycosyltransferase family 4 protein -
ACAN_RS04505 908326..910056 + 1731 WP_099333968.1 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11241.14 Da        Isoelectric Point: 10.2633

>T136039 WP_099333964.1 NZ_CP042812:906157-906441 [Malaciobacter canalis]
MSYFLDFHPKALKEWKSLNHSIKVQFHKKLKERLENPKIPKDKLSGYDNVYKIKLRNIGYGLAYEVKEKEIIVYVVSVGK
RENNKVYENLKDRV

Download         Length: 285 bp

>T136039 NZ_CP042812:906157-906441 [Malaciobacter canalis]
ATGAGCTACTTTCTTGATTTTCATCCAAAAGCTTTAAAAGAATGGAAAAGTCTAAATCACTCCATAAAAGTACAGTTTCA
TAAAAAATTAAAAGAGCGACTTGAAAATCCAAAAATACCAAAAGATAAACTCAGCGGTTATGATAATGTTTATAAAATTA
AACTTCGTAATATTGGTTATGGGCTAGCGTATGAAGTAAAAGAGAAAGAAATAATAGTCTATGTTGTGAGTGTAGGAAAA
AGAGAAAACAATAAAGTATATGAGAATTTGAAAGATAGAGTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9676.10 Da        Isoelectric Point: 4.4929

>AT136039 WP_099333963.1 NZ_CP042812:905916-906173 [Malaciobacter canalis]
MQPVLANYTASITELKKSPTQLLKDAGDETVAILNHNVASAYLVPSSVYKKMMEVMDEYYLSKEVEERLKDNEKPIRVEL
DELLS

Download         Length: 258 bp

>AT136039 NZ_CP042812:905916-906173 [Malaciobacter canalis]
ATGCAACCTGTATTAGCAAATTATACAGCAAGTATAACAGAACTGAAAAAATCACCAACACAGCTACTAAAAGATGCAGG
TGATGAAACAGTGGCGATACTTAATCACAATGTAGCAAGTGCTTATTTAGTACCTAGTAGTGTGTATAAAAAAATGATGG
AAGTTATGGATGAATATTATTTGAGTAAAGAAGTGGAAGAGAGGCTCAAAGACAATGAAAAACCAATAAGAGTAGAACTA
GATGAGCTACTTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References