Detailed information of TA system TA136038

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 17405..18075
• Replicon: plasmid unnamed3
• Accession: NZ_CP042811
• Organism: Acetobacter oryzoeni strain B6

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: EOV40_RS14865
• Protein ID: WP_128106505.1
• Coordinates: 17653..18075 (+)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: EOV40_RS14860
• Protein ID: WP_128106504.1
• Coordinates: 17405..17656 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EOV40_RS14840	12827..13435	-	609	WP_128106501.1	CatB-related O-acetyltransferase	-
EOV40_RS14845	13504..13743	-	240	WP_128106502.1	conjugal transfer protein TraD	-
EOV40_RS14850	13808..14101	-	294	WP_128106513.1	conjugal transfer protein TraD	-
EOV40_RS14855	14265..17339	+	3075	WP_128106503.1	Ti-type conjugative transfer relaxase TraA	-
EOV40_RS14860	17405..17656	+	252	WP_128106504.1	plasmid stabilization protein	Antitoxin
EOV40_RS14865	17653..18075	+	423	WP_128106505.1	type II toxin-antitoxin system VapC family toxin	Toxin
EOV40_RS14870	18075..18746	+	672	WP_128106506.1	hypothetical protein	-
EOV40_RS14875	18958..20859	-	1902	WP_128106507.1	Hint domain-containing protein	-
EOV40_RS14880	21183..21662	-	480	Protein_24	transposase	-
EOV40_RS14885	21797..22621	-	825	WP_070324343.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..29595	29595

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-122)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15307.63 Da
• Isoelectric Point: 5.8944

>T136038 WP_128106505.1 NZ_CP042811:17653-18075 [Acetobacter oryzoeni]
MILLDTNVISEPWKPAPEPRVLAWIDAQAIETLFLSAVTVAELRFGIGAMPVGRRRSVLHERLEQQVLPLFEGRVLSFDL
AASQAYAELMVRARSEGRAIGKADGYIAATAASRSYVVASRDVSPFEAAGVRVLNPWTDV

Nucleotide

• Length: 423 bp

>T136038 NZ_CP042811:17653-18075 [Acetobacter oryzoeni]
ATGATCCTGCTTGATACCAATGTGATCTCCGAGCCGTGGAAGCCTGCTCCTGAACCGCGTGTCCTGGCGTGGATTGATGC
GCAGGCGATCGAGACGCTTTTTCTGTCTGCCGTCACGGTAGCGGAATTGCGTTTCGGGATCGGGGCGATGCCGGTCGGTC
GGCGGCGTTCGGTGCTTCATGAGCGGCTGGAGCAGCAGGTTCTGCCTCTCTTCGAAGGGCGTGTCCTGTCGTTCGATCTG
GCAGCGTCACAGGCTTATGCCGAGCTGATGGTGCGGGCCAGATCTGAAGGACGTGCGATCGGCAAGGCGGATGGATATAT
TGCCGCGACCGCCGCGTCCCGCAGTTATGTCGTGGCCAGTCGTGATGTGTCGCCTTTCGAGGCGGCTGGTGTGCGGGTTC
TCAATCCGTGGACGGATGTCTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9145.45 Da
• Isoelectric Point: 9.1686

>AT136038 WP_128106504.1 NZ_CP042811:17405-17656 [Acetobacter oryzoeni]
MSSVVIRNLPEETHRALKAQAMLHGRSTEAEIRTILEAAVRPSHRVRLGSLLASIGREAGVREQDVTTLQVRDQTPAAPM
SFE

Nucleotide

• Length: 252 bp

>AT136038 NZ_CP055219:3856612-3856905 [Shigella flexneri]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATTACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGAGCT
GAAAAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA