Detailed information of TA system TA136033

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 2096118..2097295
• Replicon: chromosome
• Accession: NZ_CP042808
• Organism: Acetobacter oryzoeni strain B6

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: -
• Locus tag: EOV40_RS09605
• Protein ID: WP_128105784.1
• Coordinates: 2096118..2096420 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: EOV40_RS09610
• Protein ID: WP_128105785.1
• Coordinates: 2096441..2097295 (+)
• Length: 285 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EOV40_RS09595	2092021..2093649	-	1629	WP_128105782.1	glycogen synthase GlgA	-
EOV40_RS09600	2093861..2095981	+	2121	WP_128105783.1	glycogen debranching protein GlgX	-
EOV40_RS09605	2096118..2096420	+	303	WP_128105784.1	plasmid stabilization protein	Toxin
EOV40_RS09610	2096441..2097295	+	855	WP_128105785.1	SDR family oxidoreductase	Antitoxin
EOV40_RS09615	2097376..2099163	-	1788	WP_128105786.1	thiamine pyrophosphate-requiring protein	-
EOV40_RS09620	2099248..2100708	-	1461	WP_128105787.1	FAD-dependent monooxygenase	-
EOV40_RS09625	2100871..2101536	+	666	WP_128105788.1	SCO family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2087951..2101536	13585

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 10827.86 Da
• Isoelectric Point: 10.9935

>T136033 WP_128105784.1 NZ_CP042808:2096118-2096420 [Acetobacter oryzoeni]
MPRGDKSTYTDKQKRQAEHIEKSYEQHGVSEKEAERRAWATVNKETGGGKKSGSGRGHPVTHAPSRKGGKAGGEASAHRT
AEERSASARKAAQTRKKNST

Nucleotide

• Length: 303 bp

>T136033 NZ_CP042808:2096118-2096420 [Acetobacter oryzoeni]
ATGCCTCGTGGTGACAAATCTACTTACACAGACAAGCAAAAACGACAAGCTGAACATATCGAAAAAAGCTATGAGCAACA
TGGTGTCAGTGAAAAGGAAGCTGAACGCCGGGCTTGGGCTACGGTTAACAAAGAAACCGGTGGCGGCAAGAAAAGTGGAT
CAGGAAGAGGCCATCCCGTAACACATGCTCCCTCACGCAAAGGTGGCAAAGCAGGTGGAGAGGCCTCCGCCCACCGGACG
GCAGAAGAGCGCTCTGCCTCTGCACGAAAAGCCGCTCAAACTCGCAAGAAAAATTCAACATAA

Antitoxin

Protein

• Length: 285 a.a.
• Molecular weight: 30551.74 Da
• Isoelectric Point: 5.6404

>AT136033 WP_128105785.1 NZ_CP042808:2096441-2097295 [Acetobacter oryzoeni]
MMVHEERIPPQHQTVPGETDKMNPIPDHGEESYRGSGKLSGKVALITGADSGIGRAVAIAFAREGADIAIAYYTEDKDAQ
TTAEWVEKAGRRVILLPGDIRLRSHCNDIIKRTIDAFGNLNILVNNAAHQKSIKDLSEIDEEELDTTFRTNFYGMFFLCQ
AALPYLSSGASIINTTSINAVQPSPHLPVYAATKAAISNFTAGLAQMLGEKNIRVNAVAPGPVWTPLIPSTMPQEEIAKF
GKNTPLGRPAQPAELASAYVMFASDEASYTTGAVLPVTGGRPML

Nucleotide

• Length: 855 bp

>AT136033 NZ_CP042808:2096441-2097295 [Acetobacter oryzoeni]
ATGATGGTACATGAAGAAAGAATTCCCCCTCAACATCAGACAGTTCCTGGTGAAACAGACAAAATGAATCCTATCCCCGA
TCATGGAGAAGAAAGTTATCGAGGATCTGGAAAGCTTTCTGGCAAAGTTGCTTTGATAACAGGAGCAGATTCTGGAATAG
GTCGAGCAGTTGCCATTGCTTTTGCACGTGAAGGTGCAGATATTGCAATTGCTTATTATACAGAAGACAAAGATGCTCAG
ACAACAGCTGAATGGGTAGAAAAAGCCGGGCGCCGCGTAATCTTACTCCCGGGAGATATTCGATTACGCTCACATTGTAA
CGATATTATAAAACGCACAATAGATGCATTCGGAAATCTCAATATTTTGGTAAACAATGCGGCTCATCAAAAATCTATTA
AAGATCTTTCCGAAATTGATGAAGAAGAGCTTGATACTACGTTCCGTACAAATTTTTACGGTATGTTTTTTCTCTGTCAG
GCAGCTTTGCCATATTTAAGCAGTGGTGCTTCGATTATTAACACCACTTCGATCAACGCTGTACAACCATCTCCACATTT
GCCTGTCTATGCTGCCACAAAAGCAGCTATTTCCAATTTTACAGCGGGCCTTGCCCAAATGTTGGGAGAAAAAAATATTC
GTGTAAATGCCGTTGCACCTGGTCCAGTTTGGACACCTCTTATTCCATCAACAATGCCGCAGGAAGAGATTGCCAAATTT
GGTAAAAACACTCCTCTTGGCCGGCCAGCACAACCAGCAGAACTCGCTTCTGCCTACGTCATGTTCGCTTCAGATGAAGC
AAGTTACACAACAGGCGCTGTTCTTCCCGTAACTGGCGGAAGACCTATGCTTTAG