Detailed information of TA system TA136031

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5811205..5811814
• Replicon: chromosome
• Accession: NZ_CP042804
• Organism: Pseudomonas amygdali pv. tabaci str. ATCC 11528

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PSYTB_RS27325
• Protein ID: WP_080164823.1
• Coordinates: 5811205..5811585 (-)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A3M6GEZ6
• Locus tag: PSYTB_RS27330
• Protein ID: WP_005746660.1
• Coordinates: 5811575..5811814 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSYTB_RS27295	5806349..5806879	+	531	WP_044299855.1	nucleotidyltransferase family protein	-
PSYTB_RS27300	5807109..5807723	-	615	WP_005746667.1	histidine phosphatase family protein	-
PSYTB_RS27305	5807827..5808168	-	342	WP_005746665.1	hypothetical protein	-
PSYTB_RS27310	5808358..5808780	+	423	WP_005746664.1	DUF1493 family protein	-
PSYTB_RS27315	5809332..5810417	+	1086	WP_005746663.1	type I restriction enzyme HsdR N-terminal domain-containing protein	-
PSYTB_RS27320	5810561..5811298	+	738	WP_005746662.1	hypothetical protein	-
PSYTB_RS27325	5811205..5811585	-	381	WP_080164823.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PSYTB_RS27330	5811575..5811814	-	240	WP_005746660.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PSYTB_RS27335	5811978..5812451	-	474	WP_005746659.1	GNAT family N-acetyltransferase	-
PSYTB_RS27340	5812552..5813100	-	549	WP_005746658.1	GNAT family N-acetyltransferase	-
PSYTB_RS27345	5813260..5813754	+	495	WP_004667254.1	hypothetical protein	-
PSYTB_RS27350	5813788..5815062	-	1275	WP_004667253.1	OprD family porin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-81)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-70)

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 13873.07 Da
• Isoelectric Point: 8.6903

>T136031 WP_080164823.1 NZ_CP042804:c5811585-5811205 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MTYNLELDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RECPPATADESLTGVDQPSVAAFLAARAASIAASVSWVCSSPLYAS

Nucleotide

• Length: 381 bp

>T136031 NZ_CP042804:c5811585-5811205 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
ATGACCTATAACCTCGAACTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAATGTCCGCCCGCAACGGCTGACGAGTCGCTGACTGGTGTTGATCAACCCTCAGTGGCGGCCTTTTTGGCCGCACG
TGCAGCGAGCATCGCCGCTTCCGTTTCCTGGGTGTGCAGCTCACCTTTGTACGCCAGTTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8999.40 Da
• Isoelectric Point: 4.6017

>AT136031 WP_005746660.1 NZ_CP042804:c5811814-5811575 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLATPQRVKISLDDL

Nucleotide

• Length: 240 bp

>AT136031 NZ_CP055219:c1984905-1984639 [Shigella flexneri]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A3M6GEZ6