Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 5289198..5289793 Replicon chromosome
Accession NZ_CP042804
Organism Pseudomonas amygdali pv. tabaci str. ATCC 11528

Toxin (Protein)


Gene name relE Uniprot ID A0A0Q0BQQ0
Locus tag PSYTB_RS24600 Protein ID WP_005782087.1
Coordinates 5289198..5289500 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9S822
Locus tag PSYTB_RS24605 Protein ID WP_005746689.1
Coordinates 5289503..5289793 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSYTB_RS24580 5284531..5285871 - 1341 WP_016982358.1 precorrin-3B synthase -
PSYTB_RS24585 5285997..5287199 + 1203 WP_005746695.1 bifunctional cobalt-precorrin-7 (C(5))-methyltransferase/cobalt-precorrin-6B (C(15))-methyltransferase -
PSYTB_RS24590 5287199..5288311 + 1113 WP_005746694.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PSYTB_RS24595 5288308..5289048 + 741 WP_005746691.1 cobalt-precorrin-6A reductase -
PSYTB_RS24600 5289198..5289500 + 303 WP_005782087.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSYTB_RS24605 5289503..5289793 + 291 WP_005746689.1 putative addiction module antidote protein Antitoxin
PSYTB_RS24610 5289864..5290325 + 462 WP_002555389.1 copper chaperone PCu(A)C -
PSYTB_RS24615 5290339..5290773 + 435 WP_016982355.1 DUF2946 domain-containing protein -
PSYTB_RS24620 5290858..5292231 + 1374 WP_005746685.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-86)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11507.24 Da        Isoelectric Point: 10.6008

>T136029 WP_005782087.1 NZ_CP042804:5289198-5289500 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MNRFEQTPAFAEWLRSLKDSIGRARILARIRAAELGNFGDCDALGQGVRELRIHHGPGYRVYFTRRTGVVYLLLIAGDKS
SQKRDIKFARQLARELCERE

Download         Length: 303 bp

>T136029 NZ_CP042804:5289198-5289500 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
ATGAATCGCTTTGAACAGACGCCCGCTTTTGCGGAGTGGTTAAGGTCGTTGAAGGACTCCATTGGCAGAGCTCGAATTCT
GGCTCGAATAAGAGCAGCAGAGCTCGGTAACTTCGGGGACTGCGATGCTTTAGGTCAAGGCGTCAGAGAGCTACGAATAC
ACCATGGACCAGGTTATCGGGTGTATTTTACCCGACGCACGGGTGTGGTTTACCTGCTCTTGATCGCTGGTGACAAATCG
TCTCAAAAGCGCGACATAAAATTTGCCAGACAGCTGGCGAGAGAGCTCTGTGAGAGGGAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10500.87 Da        Isoelectric Point: 4.5720

>AT136029 WP_005746689.1 NZ_CP042804:5289503-5289793 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MNNETTPFDTVDYLKTPEDMANYLDACLEEDSGDGLLVRAALNDIARAYGMTQIARDTGLGRESLYKALGANGNPEFTTI
MKVVRAMGIKLHASTR

Download         Length: 291 bp

>AT136029 NZ_CP042804:5289503-5289793 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
ATGAACAACGAGACGACACCGTTCGATACCGTCGACTATTTGAAGACACCTGAAGATATGGCCAATTATCTGGATGCGTG
TCTTGAAGAGGATTCAGGAGACGGGCTGCTCGTAAGGGCCGCGCTGAACGACATAGCAAGGGCTTATGGCATGACACAAA
TCGCACGTGATACAGGTCTTGGTCGTGAGAGCCTCTACAAAGCGCTGGGTGCAAACGGTAATCCAGAGTTCACGACCATC
ATGAAAGTCGTGAGGGCGATGGGGATCAAACTACACGCAAGTACGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0Q0BQQ0

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9S822

References