Detailed information of TA system TA136028

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 1997537..1998050
• Replicon: chromosome
• Accession: NZ_CP042804
• Organism: Pseudomonas amygdali pv. tabaci str. ATCC 11528

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PSYTB_RS09635
• Protein ID: WP_005783115.1
• Coordinates: 1997537..1997821 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0N8T2X1
• Locus tag: PSYTB_RS09640
• Protein ID: WP_029241049.1
• Coordinates: 1997811..1998050 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSYTB_RS09620	1993680..1995608	+	1929	WP_010198401.1	methyl-accepting chemotaxis protein	-
PSYTB_RS09625	1995639..1996571	-	933	WP_039847441.1	DMT family transporter	-
PSYTB_RS09630	1996646..1997500	+	855	WP_004658390.1	LysR family transcriptional regulator	-
PSYTB_RS09635	1997537..1997821	-	285	WP_005783115.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PSYTB_RS09640	1997811..1998050	-	240	WP_029241049.1	CopG family ribbon-helix-helix protein	Antitoxin
PSYTB_RS09645	1998210..1999226	-	1017	WP_002552793.1	1-aminocyclopropane-1-carboxylate deaminase	-
PSYTB_RS09650	1999413..1999919	+	507	WP_004658394.1	Lrp/AsnC family transcriptional regulator	-
PSYTB_RS09655	2000069..2000977	+	909	WP_005744311.1	DUF808 domain-containing protein	-
PSYTB_RS09665	2001156..2001941	-	786	WP_002552796.1	membrane protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10628.27 Da
• Isoelectric Point: 10.0899

>T136028 WP_005783115.1 NZ_CP042804:c1997821-1997537 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYHIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T136028 NZ_CP042804:c1997821-1997537 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
ATGCAGGTTGAGTGGCTTAAAACGGCGCTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACAGGACAATCCAGCTGC
TGCCGCAGCTTTCGTGAAAGCAATTCAATCAAGCGTGACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCACATCCGTAGCGGCCGGCTACAGGTT
CTAAGGATTTTCCACACCAGAAGACAATCGCCCCCCGTGTGGTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8715.80 Da
• Isoelectric Point: 4.4354

>AT136028 WP_029241049.1 NZ_CP042804:c1998050-1997811 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFANTEDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT136028 NZ_CP042804:c1998050-1997811 [Pseudomonas amygdali pv. tabaci str. ATCC 11528]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCGGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACTCGCGAGGCATGGCAGATTGCCGAAATTCAGCGCGCGATTG
AAGAAGCCGACGCTGGCGAGTTCGCCAATACAGAGGACGTAAAAGCTGTCATGGACAAATGGTCTGGCAATGCAGGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A0N8T2X1