Detailed information of TA system TA136026

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2605905..2606430
• Replicon: chromosome
• Accession: NZ_CP042652
• Organism: Pseudoarcobacter acticola strain KCTC 52212

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AACT_RS13290
• Protein ID: WP_172127653.1
• Coordinates: 2605905..2606189 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AACT_RS13295
• Protein ID: WP_172127655.1
• Coordinates: 2606179..2606430 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AACT_RS13265	2601631..2601864	+	234	WP_172127643.1	hypothetical protein	-
AACT_RS13270	2601848..2602252	+	405	WP_172127645.1	ester cyclase	-
AACT_RS13275	2602277..2602987	+	711	WP_172127647.1	2OG-Fe(II) oxygenase	-
AACT_RS13280	2603042..2603776	+	735	WP_172127649.1	phytanoyl-CoA dioxygenase family protein	-
AACT_RS13285	2603769..2605880	+	2112	WP_172127651.1	helix-hairpin-helix domain-containing protein	-
AACT_RS13290	2605905..2606189	-	285	WP_172127653.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AACT_RS13295	2606179..2606430	-	252	WP_172127655.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
AACT_RS13300	2606687..2607745	-	1059	WP_172127657.1	hypothetical protein	-
AACT_RS13305	2607764..2608123	-	360	WP_172128699.1	DUF4238 domain-containing protein	-
AACT_RS13310	2608464..2608652	-	189	WP_172127659.1	DUF4238 domain-containing protein	-
AACT_RS13315	2608706..2609011	-	306	WP_172127661.1	CcdB family protein	-
AACT_RS13320	2609011..2609256	-	246	WP_172127663.1	type II toxin-antitoxin system CcdA family antitoxin	-
AACT_RS13325	2609393..2609776	-	384	WP_172127665.1	Rid family detoxifying hydrolase	-
AACT_RS13330	2609805..2610590	-	786	WP_172127667.1	NUDIX domain-containing protein	-
AACT_RS13335	2610618..2611232	-	615	WP_172127669.1	LysE family transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11228.14 Da
• Isoelectric Point: 10.3190

>T136026 WP_172127653.1 NZ_CP042652:c2606189-2605905 [Pseudoarcobacter acticola]
MTYNLEFKPKALKEWSKLGSTIKEQFKNKLKERLENPRVEKDKLSGYENVYKIKLRTVGYRLAYEVKDEEIIVLVLSVGK
RENDKIYKNLKGRF

Nucleotide

• Length: 285 bp

>T136026 NZ_CP042652:c2606189-2605905 [Pseudoarcobacter acticola]
ATGACTTATAATCTTGAATTTAAACCTAAAGCTTTAAAAGAATGGAGTAAATTAGGGTCTACTATAAAAGAACAATTCAA
AAATAAGTTAAAAGAGAGATTAGAAAATCCAAGAGTAGAAAAAGATAAACTAAGCGGATATGAAAATGTTTATAAAATCA
AATTAAGAACAGTTGGTTATAGACTTGCCTATGAAGTAAAAGATGAAGAAATAATCGTTCTTGTACTAAGTGTTGGAAAA
AGAGAAAATGATAAAATTTACAAAAATTTAAAAGGTAGATTTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9373.80 Da
• Isoelectric Point: 4.5219

>AT136026 WP_172127655.1 NZ_CP042652:c2606430-2606179 [Pseudoarcobacter acticola]
MQAILAKYTASITELKKSPTQLLNQADNEVIAILNHNIPSAYLVPSKLYEKMMDIIDDYHLSLEVEKSLKDSDTPIKVNL
DDL

Nucleotide

• Length: 252 bp

>AT136026 NZ_CP042652:c2606430-2606179 [Pseudoarcobacter acticola]
ATGCAAGCAATTTTAGCAAAGTATACGGCCAGTATTACTGAACTTAAAAAGTCTCCTACTCAATTGCTAAATCAAGCAGA
TAATGAAGTTATCGCAATTTTAAATCATAATATTCCAAGTGCTTATTTGGTTCCAAGTAAATTATATGAAAAAATGATGG
ATATTATAGATGATTATCATTTATCTCTTGAAGTTGAAAAATCTCTAAAGGATTCAGATACACCAATTAAAGTAAACTTA
GATGACTTATAA