Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 1011536..1012173 Replicon chromosome
Accession NZ_CP042652
Organism Pseudoarcobacter acticola strain KCTC 52212

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AACT_RS05290 Protein ID WP_172125634.1
Coordinates 1011772..1012173 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AACT_RS05285 Protein ID WP_172125632.1
Coordinates 1011536..1011775 (+) Length 80 a.a.

Genomic Context

AACT_RS05260AACT_RS05265AACT_RS05270AACT_RS05285AACT_RS05290AACT_RS05310AACT_RS05275AACT_RS05280AACT_RS05295AACT_RS05300AACT_RS05305
Location: 1006589..1007824 (1236 bp)
Type: Others
Protein ID: WP_172125624.1
Location: 1008028..1009668 (1641 bp)
Type: Others
Protein ID: WP_172125626.1
Location: 1009705..1010025 (321 bp)
Type: Others
Protein ID: Protein_1032
Location: 1011536..1011775 (240 bp)
Type: Antitoxin
Protein ID: WP_172125632.1
Location: 1011772..1012173 (402 bp)
Type: Toxin
Protein ID: WP_172125634.1
Location: 1014772..1016046 (1275 bp)
Type: Others
Protein ID: WP_172125640.1
Location: 1010075..1010485 (411 bp)
Type: Others
Protein ID: WP_172125628.1
Location: 1010496..1011395 (900 bp)
Type: Others
Protein ID: WP_172125630.1
Location: 1012180..1012731 (552 bp)
Type: Others
Protein ID: Protein_1037
Location: 1012816..1014105 (1290 bp)
Type: Others
Protein ID: WP_172125636.1
Location: 1014165..1014527 (363 bp)
Type: Others
Protein ID: WP_172125638.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AACT_RS052601006589..1007824+1236WP_172125624.1chemotaxis protein-
AACT_RS052651008028..1009668+1641WP_172125626.1IS1634 family transposase-
AACT_RS052701009705..1010025+321Protein_1032methyl-accepting chemotaxis protein-
AACT_RS052751010075..1010485-411WP_172125628.1NUDIX hydrolase-
AACT_RS052801010496..1011395-900WP_172125630.1polyphosphate kinase 2-
AACT_RS052851011536..1011775+240WP_172125632.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
AACT_RS052901011772..1012173+402WP_172125634.1type II toxin-antitoxin system VapC family toxinToxin
AACT_RS052951012180..1012731-552Protein_1037DNA-binding protein-
AACT_RS053001012816..1014105-1290WP_172125636.1IS1380 family transposase-
AACT_RS053051014165..1014527-363WP_172125638.1virulence RhuM family protein-
AACT_RS053101014772..1016046+1275WP_172125640.1urea ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(8-51)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15323.97 Da        Isoelectric Point: 7.2421

>T136025 WP_172125634.1 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
MKKLILDTNICIYIIKNKPQSLREKFREFDVGDLCISSITVSELYFAAYKSLHIEKNLLALEHFLRPFDILEYDLNASIE
YGKIRATLEKSGKVIGGLNMMIAAHALSNKMTLVTNNIKEFERIENLVLDNWV

Download         Length: 402 bp

>T136025 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
TTGAAAAAGTTAATACTTGATACAAATATTTGTATTTATATTATAAAAAATAAACCTCAAAGTTTAAGGGAAAAATTCAG
AGAGTTTGATGTAGGCGATTTATGTATTTCATCTATTACGGTTTCCGAGCTTTATTTTGCAGCTTATAAAAGTTTGCATA
TTGAGAAAAATCTTTTAGCACTTGAACATTTTTTAAGACCTTTTGATATATTAGAATATGACTTAAATGCTTCTATTGAG
TATGGAAAAATAAGAGCAACTTTAGAAAAATCTGGAAAAGTAATCGGTGGACTTAATATGATGATAGCCGCTCATGCTTT
GTCAAATAAAATGACTTTAGTTACAAATAACATTAAAGAGTTTGAAAGAATTGAAAATTTGGTTTTGGATAATTGGGTTT
AA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9414.66 Da        Isoelectric Point: 5.1088

>AT136025 WP_172125632.1 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
MTAIAKIFKNGQSQAVRLPKEFRFENQNELFVKKVENGIILLSKNDKSVWDNMFNRLDEFSDDFMNERVQPTQNREDLF

Download         Length: 240 bp

>AT136025 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
ATGACAGCAATAGCAAAAATATTTAAAAATGGTCAAAGTCAAGCTGTTAGATTACCAAAAGAGTTTAGATTTGAAAATCA
AAATGAACTTTTTGTTAAAAAAGTTGAAAATGGAATAATATTACTTTCTAAAAATGATAAATCAGTTTGGGATAATATGT
TTAATAGACTAGATGAATTTTCAGATGATTTTATGAATGAGCGAGTTCAACCAACTCAAAATAGGGAGGATTTATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References