Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 1011536..1012173 Replicon chromosome
Accession NZ_CP042652
Organism Pseudoarcobacter acticola strain KCTC 52212

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AACT_RS05290 Protein ID WP_172125634.1
Coordinates 1011772..1012173 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AACT_RS05285 Protein ID WP_172125632.1
Coordinates 1011536..1011775 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AACT_RS05260 1006589..1007824 + 1236 WP_172125624.1 chemotaxis protein -
AACT_RS05265 1008028..1009668 + 1641 WP_172125626.1 IS1634 family transposase -
AACT_RS05270 1009705..1010025 + 321 Protein_1032 methyl-accepting chemotaxis protein -
AACT_RS05275 1010075..1010485 - 411 WP_172125628.1 NUDIX hydrolase -
AACT_RS05280 1010496..1011395 - 900 WP_172125630.1 polyphosphate kinase 2 -
AACT_RS05285 1011536..1011775 + 240 WP_172125632.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
AACT_RS05290 1011772..1012173 + 402 WP_172125634.1 type II toxin-antitoxin system VapC family toxin Toxin
AACT_RS05295 1012180..1012731 - 552 Protein_1037 DNA-binding protein -
AACT_RS05300 1012816..1014105 - 1290 WP_172125636.1 IS1380 family transposase -
AACT_RS05305 1014165..1014527 - 363 WP_172125638.1 virulence RhuM family protein -
AACT_RS05310 1014772..1016046 + 1275 WP_172125640.1 urea ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(8-51)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15323.97 Da        Isoelectric Point: 7.2421

>T136025 WP_172125634.1 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
MKKLILDTNICIYIIKNKPQSLREKFREFDVGDLCISSITVSELYFAAYKSLHIEKNLLALEHFLRPFDILEYDLNASIE
YGKIRATLEKSGKVIGGLNMMIAAHALSNKMTLVTNNIKEFERIENLVLDNWV

Download         Length: 402 bp

>T136025 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
TTGAAAAAGTTAATACTTGATACAAATATTTGTATTTATATTATAAAAAATAAACCTCAAAGTTTAAGGGAAAAATTCAG
AGAGTTTGATGTAGGCGATTTATGTATTTCATCTATTACGGTTTCCGAGCTTTATTTTGCAGCTTATAAAAGTTTGCATA
TTGAGAAAAATCTTTTAGCACTTGAACATTTTTTAAGACCTTTTGATATATTAGAATATGACTTAAATGCTTCTATTGAG
TATGGAAAAATAAGAGCAACTTTAGAAAAATCTGGAAAAGTAATCGGTGGACTTAATATGATGATAGCCGCTCATGCTTT
GTCAAATAAAATGACTTTAGTTACAAATAACATTAAAGAGTTTGAAAGAATTGAAAATTTGGTTTTGGATAATTGGGTTT
AA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9414.66 Da        Isoelectric Point: 5.1088

>AT136025 WP_172125632.1 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
MTAIAKIFKNGQSQAVRLPKEFRFENQNELFVKKVENGIILLSKNDKSVWDNMFNRLDEFSDDFMNERVQPTQNREDLF

Download         Length: 240 bp

>AT136025 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
ATGACAGCAATAGCAAAAATATTTAAAAATGGTCAAAGTCAAGCTGTTAGATTACCAAAAGAGTTTAGATTTGAAAATCA
AAATGAACTTTTTGTTAAAAAAGTTGAAAATGGAATAATATTACTTTCTAAAAATGATAAATCAGTTTGGGATAATATGT
TTAATAGACTAGATGAATTTTCAGATGATTTTATGAATGAGCGAGTTCAACCAACTCAAAATAGGGAGGATTTATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References