Detailed information of TA system TA136025

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-MazE
• Location: 1011536..1012173
• Replicon: chromosome
• Accession: NZ_CP042652
• Organism: Pseudoarcobacter acticola strain KCTC 52212

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AACT_RS05290
• Protein ID: WP_172125634.1
• Coordinates: 1011772..1012173 (+)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: AACT_RS05285
• Protein ID: WP_172125632.1
• Coordinates: 1011536..1011775 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AACT_RS05260	1006589..1007824	+	1236	WP_172125624.1	chemotaxis protein	-
AACT_RS05265	1008028..1009668	+	1641	WP_172125626.1	IS1634 family transposase	-
AACT_RS05270	1009705..1010025	+	321	Protein_1032	methyl-accepting chemotaxis protein	-
AACT_RS05275	1010075..1010485	-	411	WP_172125628.1	NUDIX hydrolase	-
AACT_RS05280	1010496..1011395	-	900	WP_172125630.1	polyphosphate kinase 2	-
AACT_RS05285	1011536..1011775	+	240	WP_172125632.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
AACT_RS05290	1011772..1012173	+	402	WP_172125634.1	type II toxin-antitoxin system VapC family toxin	Toxin
AACT_RS05295	1012180..1012731	-	552	Protein_1037	DNA-binding protein	-
AACT_RS05300	1012816..1014105	-	1290	WP_172125636.1	IS1380 family transposase	-
AACT_RS05305	1014165..1014527	-	363	WP_172125638.1	virulence RhuM family protein	-
AACT_RS05310	1014772..1016046	+	1275	WP_172125640.1	urea ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-125)

Antitoxin

• SpoVT-AbrB domain (8-51)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 15323.97 Da
• Isoelectric Point: 7.2421

>T136025 WP_172125634.1 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
MKKLILDTNICIYIIKNKPQSLREKFREFDVGDLCISSITVSELYFAAYKSLHIEKNLLALEHFLRPFDILEYDLNASIE
YGKIRATLEKSGKVIGGLNMMIAAHALSNKMTLVTNNIKEFERIENLVLDNWV

Nucleotide

• Length: 402 bp

>T136025 NZ_CP042652:1011772-1012173 [Pseudoarcobacter acticola]
TTGAAAAAGTTAATACTTGATACAAATATTTGTATTTATATTATAAAAAATAAACCTCAAAGTTTAAGGGAAAAATTCAG
AGAGTTTGATGTAGGCGATTTATGTATTTCATCTATTACGGTTTCCGAGCTTTATTTTGCAGCTTATAAAAGTTTGCATA
TTGAGAAAAATCTTTTAGCACTTGAACATTTTTTAAGACCTTTTGATATATTAGAATATGACTTAAATGCTTCTATTGAG
TATGGAAAAATAAGAGCAACTTTAGAAAAATCTGGAAAAGTAATCGGTGGACTTAATATGATGATAGCCGCTCATGCTTT
GTCAAATAAAATGACTTTAGTTACAAATAACATTAAAGAGTTTGAAAGAATTGAAAATTTGGTTTTGGATAATTGGGTTT
AA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9414.66 Da
• Isoelectric Point: 5.1088

>AT136025 WP_172125632.1 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
MTAIAKIFKNGQSQAVRLPKEFRFENQNELFVKKVENGIILLSKNDKSVWDNMFNRLDEFSDDFMNERVQPTQNREDLF

Nucleotide

• Length: 240 bp

>AT136025 NZ_CP042652:1011536-1011775 [Pseudoarcobacter acticola]
ATGACAGCAATAGCAAAAATATTTAAAAATGGTCAAAGTCAAGCTGTTAGATTACCAAAAGAGTTTAGATTTGAAAATCA
AAATGAACTTTTTGTTAAAAAAGTTGAAAATGGAATAATATTACTTTCTAAAAATGATAAATCAGTTTGGGATAATATGT
TTAATAGACTAGATGAATTTTCAGATGATTTTATGAATGAGCGAGTTCAACCAACTCAAAATAGGGAGGATTTATTTTGA