Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-RHH
Location 2736510..2736972 Replicon chromosome
Accession NZ_CP042596
Organism Granulicella sp. WH15

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag FTO74_RS11375 Protein ID WP_162538259.1
Coordinates 2736510..2736773 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag FTO74_RS11380 Protein ID WP_162538260.1
Coordinates 2736760..2736972 (-) Length 71 a.a.

Genomic Context

FTO74_RS11365FTO74_RS11395FTO74_RS11400FTO74_RS11370FTO74_RS11375FTO74_RS11380FTO74_RS11385FTO74_RS11390
Location: 2731810..2732628 (819 bp)
Type: Others
Protein ID: WP_162538257.1
Location: 2738885..2739826 (942 bp)
Type: Others
Protein ID: WP_162538263.1
Location: 2739826..2740251 (426 bp)
Type: Others
Protein ID: WP_162538264.1
Location: 2733209..2736496 (3288 bp)
Type: Others
Protein ID: WP_162538258.1
Location: 2736510..2736773 (264 bp)
Type: Toxin
Protein ID: WP_162538259.1
Location: 2736760..2736972 (213 bp)
Type: Antitoxin
Protein ID: WP_162538260.1
Location: 2737004..2738137 (1134 bp)
Type: Others
Protein ID: WP_162538261.1
Location: 2738499..2738825 (327 bp)
Type: Others
Protein ID: WP_162538262.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FTO74_RS113652731810..2732628+819WP_162538257.1EcsC family protein-
FTO74_RS113702733209..2736496-3288WP_162538258.1carbamoyl-phosphate synthase large subunit-
FTO74_RS113752736510..2736773-264WP_162538259.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FTO74_RS113802736760..2736972-213WP_162538260.1ribbon-helix-helix protein, CopG familyAntitoxin
FTO74_RS113852737004..2738137-1134WP_162538261.1glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit-
FTO74_RS113902738499..2738825-327WP_162538262.1Rieske 2Fe-2S domain-containing protein-
FTO74_RS113952738885..2739826+942WP_162538263.1alpha/beta hydrolase-
FTO74_RS114002739826..2740251+426WP_162538264.1DoxX family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10327.99 Da        Isoelectric Point: 9.8466

>T135999 WP_162538259.1 NZ_CP042596:c2736773-2736510 [Granulicella sp. WH15]
VWRTEFTDVAERALLKLDKPVRERILAFFRERVSSSEDPKALAEPLAGEFRGLWRFRVGDYRVICDIRQDVLIVLVLQVG
HRREVYR

Download         Length: 264 bp

>T135999 NZ_CP042596:c2736773-2736510 [Granulicella sp. WH15]
GTGTGGCGGACTGAGTTCACCGATGTTGCGGAGCGGGCGCTGCTCAAGTTGGACAAGCCCGTACGGGAACGCATTCTGGC
CTTCTTCCGCGAGCGTGTGAGTTCGTCGGAAGACCCAAAGGCTCTCGCCGAACCGCTTGCAGGGGAGTTTCGCGGACTTT
GGAGATTTCGTGTGGGTGACTATCGCGTCATCTGCGACATACGGCAGGATGTCCTCATCGTCCTGGTACTTCAGGTGGGG
CATCGCAGGGAAGTTTATCGTTAG

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8070.96 Da        Isoelectric Point: 4.2925

>AT135999 WP_162538260.1 NZ_CP042596:c2736972-2736760 [Granulicella sp. WH15]
MIEVQLEPELEARLERLAADTHVSKSFFAHEAIQRFVEDREDYLEGIAALSQSKYAISQEEMERRSSVAD

Download         Length: 213 bp

>AT135999 NZ_CP042596:c2736972-2736760 [Granulicella sp. WH15]
ATGATCGAAGTCCAGCTTGAACCTGAACTGGAAGCACGGTTGGAGCGTCTCGCGGCTGACACGCATGTCAGCAAGAGCTT
CTTCGCTCACGAGGCGATCCAGCGATTTGTAGAAGATCGCGAAGATTACCTTGAGGGCATTGCCGCTCTCTCTCAATCCA
AGTACGCGATCTCGCAGGAAGAGATGGAGCGGCGATCGAGTGTGGCGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References