Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2071146..2072658 Replicon chromosome
Accession NZ_CP042596
Organism Granulicella sp. WH15

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag FTO74_RS08685 Protein ID WP_162537785.1
Coordinates 2071146..2072054 (-) Length 303 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag FTO74_RS08690 Protein ID WP_162537786.1
Coordinates 2072044..2072658 (-) Length 205 a.a.

Genomic Context

FTO74_RS08660FTO74_RS08665FTO74_RS08680FTO74_RS08695FTO74_RS08700FTO74_RS08710FTO74_RS08670FTO74_RS08675FTO74_RS08685FTO74_RS08690FTO74_RS08705
Location: 2066558..2067811 (1254 bp)
Type: Others
Protein ID: WP_162537781.1
Location: 2067808..2068779 (972 bp)
Type: Others
Protein ID: WP_162537782.1
Location: 2070787..2071056 (270 bp)
Type: Others
Protein ID: WP_162537784.1
Location: 2073021..2073275 (255 bp)
Type: Others
Protein ID: WP_162537787.1
Location: 2073560..2074255 (696 bp)
Type: Others
Protein ID: WP_162537788.1
Location: 2075774..2076907 (1134 bp)
Type: Others
Protein ID: WP_162537790.1
Location: 2068836..2070140 (1305 bp)
Type: Others
Protein ID: Protein_1704
Location: 2070490..2070705 (216 bp)
Type: Others
Protein ID: WP_162537783.1
Location: 2071146..2072054 (909 bp)
Type: Toxin
Protein ID: WP_162537785.1
Location: 2072044..2072658 (615 bp)
Type: Antitoxin
Protein ID: WP_162537786.1
Location: 2074625..2075410 (786 bp)
Type: Others
Protein ID: WP_162537789.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FTO74_RS086602066558..2067811+1254WP_162537781.1tyrosine-type recombinase/integrase-
FTO74_RS086652067808..2068779+972WP_162537782.1tyrosine-type recombinase/integrase-
FTO74_RS086702068836..2070140-1305Protein_1704AAA family ATPase-
FTO74_RS086752070490..2070705-216WP_162537783.1hypothetical protein-
FTO74_RS086802070787..2071056+270WP_162537784.1helix-turn-helix domain-containing protein-
FTO74_RS086852071146..2072054-909WP_162537785.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
FTO74_RS086902072044..2072658-615WP_162537786.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing proteinAntitoxin
FTO74_RS086952073021..2073275+255WP_162537787.1hypothetical protein-
FTO74_RS087002073560..2074255+696WP_162537788.1hypothetical protein-
FTO74_RS087052074625..2075410-786WP_162537789.1UPF0489 family protein-
FTO74_RS087102075774..2076907+1134WP_162537790.1restriction endonuclease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-257)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-54)


Sequences

Toxin        


Download         Length: 303 a.a.        Molecular weight: 33919.87 Da        Isoelectric Point: 5.7107

>T135998 WP_162537785.1 NZ_CP042596:c2072054-2071146 [Granulicella sp. WH15]
MPHETRNVGASVRARLLARSRAESSDYQILLTRYALERLLYRLSVSAHHDRFILKGALLFVTWLPDPFRPTRDLDLLGYG
ASTPEALADTFKAICSTPVPDDGVTFDVEGITAVPIREDVEYGGVRVRTQAIIDGARIPIQVDIGFGDVITPGPVEIDYP
ALLDSPAPHLRAYPVETVIAEKFNAMVTLGIANSRLKDFYDLWLISRTFELDRAVLFAAVQRTFEQRETPIPTDIPTGLT
DQYGEQWGMQWKAFLKREHMNAAPNDLLKLIADLRSFLVPLTIPPRTDSYWISGGPWSIRKN

Download         Length: 909 bp

>T135998 NZ_CP042596:c2072054-2071146 [Granulicella sp. WH15]
ATGCCGCATGAAACTCGTAACGTCGGAGCTTCGGTAAGGGCGAGGCTCCTCGCTCGCTCACGAGCAGAAAGCTCTGACTA
TCAAATCCTTCTGACAAGATACGCACTGGAGAGGCTGCTCTACCGGCTGAGTGTCTCCGCGCACCATGACCGCTTCATCC
TCAAGGGCGCATTGCTCTTTGTGACATGGCTTCCAGATCCATTCCGGCCAACGCGAGACCTTGATCTACTCGGCTATGGA
GCCAGCACCCCGGAGGCACTTGCCGACACCTTCAAAGCTATATGCTCAACTCCTGTTCCTGACGACGGCGTTACTTTCGA
CGTTGAGGGCATAACGGCTGTGCCGATCCGCGAAGACGTTGAGTACGGAGGGGTCCGAGTCCGTACCCAGGCGATCATCG
ACGGCGCACGCATACCCATTCAGGTAGACATCGGCTTTGGGGATGTCATCACGCCGGGGCCCGTCGAGATCGACTACCCC
GCCCTCCTCGACTCGCCAGCACCGCATCTCCGCGCCTATCCGGTTGAAACCGTAATTGCGGAAAAGTTCAACGCTATGGT
GACGCTGGGGATTGCCAATAGTCGGCTTAAAGACTTCTATGACCTTTGGCTGATCTCCCGTACCTTTGAATTGGATCGTG
CTGTTTTGTTCGCTGCTGTGCAACGAACCTTTGAGCAACGGGAAACTCCCATACCAACTGACATACCCACAGGATTGACG
GATCAATATGGGGAGCAGTGGGGTATGCAGTGGAAAGCCTTTCTAAAACGTGAGCACATGAACGCTGCGCCAAATGACCT
GCTTAAGTTGATCGCAGATTTGCGTAGCTTTCTGGTTCCATTGACGATCCCACCCCGTACAGACTCCTACTGGATCTCTG
GCGGCCCTTGGTCAATCCGCAAGAATTAG

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 23519.60 Da        Isoelectric Point: 9.3824

>AT135998 WP_162537786.1 NZ_CP042596:c2072658-2072044 [Granulicella sp. WH15]
MLATQRTRALDLLKARGMLRLRDFIAENIEPETLARLVREEQVIRPARGLYQLPDTEIEAAYMLAEASVLVPKGIVCLIS
ALQFHELTLQMPSAVWMAIERTAWRPMISYPPIRFVRFSGWAMTEGVEMYLIQSREVPITNPARTIVDCFRYRNKIGIDV
AIEGLREGIRHRKCTPDQLWQYAKKARVWTVMRPYVETVVSDAA

Download         Length: 615 bp

>AT135998 NZ_CP042596:c2072658-2072044 [Granulicella sp. WH15]
ATGCTCGCCACTCAACGAACCCGTGCTCTCGATCTTCTAAAGGCCAGAGGGATGCTTCGTCTTCGGGACTTTATTGCTGA
AAACATTGAGCCGGAGACTCTGGCGCGACTGGTCAGAGAGGAGCAAGTCATTCGCCCCGCACGTGGGCTTTACCAGCTTC
CAGATACTGAGATCGAAGCAGCTTACATGCTTGCCGAGGCTTCTGTGCTCGTGCCCAAAGGAATTGTCTGCCTCATCTCA
GCTCTCCAATTTCATGAACTGACGCTCCAGATGCCTTCCGCCGTGTGGATGGCAATCGAACGTACCGCATGGCGGCCTAT
GATCAGCTATCCGCCCATTCGCTTTGTCCGGTTTAGCGGATGGGCTATGACCGAGGGAGTAGAGATGTATCTCATTCAAT
CCCGCGAAGTCCCGATCACAAACCCTGCGCGAACCATCGTGGACTGCTTTCGGTACCGCAACAAGATTGGCATTGACGTA
GCCATAGAAGGACTGCGCGAAGGTATTCGACATCGCAAATGTACGCCGGATCAGCTTTGGCAATATGCGAAGAAAGCGCG
GGTCTGGACGGTAATGCGTCCCTATGTCGAAACGGTGGTATCCGATGCCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References