Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2840365..2840510 Replicon chromosome
Accession NZ_CP042578
Organism Enterobacter kobei strain C16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2840372..2840475 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2840365..2840510 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR825_RS13885 2835761..2835913 + 153 WP_047028424.1 DUF1317 family protein -
FR825_RS13890 2835910..2836392 + 483 WP_047028423.1 class I SAM-dependent methyltransferase -
FR825_RS13895 2836389..2837048 + 660 WP_047028422.1 DNA methyltransferase -
FR825_RS13900 2837167..2837385 + 219 WP_006809800.1 TraR/DksA family transcriptional regulator -
FR825_RS13905 2837385..2837771 + 387 WP_047028421.1 DUF2591 family protein -
FR825_RS13910 2837758..2838153 + 396 WP_047028420.1 hypothetical protein -
FR825_RS13915 2838163..2838489 + 327 WP_047028419.1 DUF550 domain-containing protein -
FR825_RS13920 2838968..2839240 + 273 WP_023330710.1 hypothetical protein -
FR825_RS13925 2839209..2840294 + 1086 WP_023330711.1 phage integrase Arm DNA-binding domain-containing protein -
- 2840365..2840510 + 146 - - Antitoxin
- 2840372..2840475 - 104 - - Toxin
FR825_RS13930 2840614..2840952 - 339 WP_014884299.1 YebY family protein -
FR825_RS13935 2840969..2841838 - 870 WP_014884300.1 copper homeostasis membrane protein CopD -
FR825_RS13940 2841840..2842211 - 372 WP_014884301.1 CopC domain-containing protein YobA -
FR825_RS13945 2842349..2842579 + 231 WP_013096102.1 DNA polymerase III subunit theta -
FR825_RS13950 2842690..2843340 + 651 WP_014884302.1 carbon-nitrogen hydrolase family protein -
FR825_RS13955 2843365..2844027 + 663 WP_014884303.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrA / gtrB 2774678..2846820 72142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T135936 NZ_CP042578:c2840475-2840372 [Enterobacter kobei]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135936 NZ_CP042578:2840365-2840510 [Enterobacter kobei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References