135815

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1165012..1165679 Replicon chromosome
Accession NZ_CP042530
Organism Klebsiella aerogenes strain C9

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag FR830_RS05750 Protein ID WP_151584431.1
Coordinates 1165012..1165341 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag FR830_RS05755 Protein ID WP_151584434.1
Coordinates 1165362..1165679 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR830_RS05715 1160399..1160692 - 294 WP_131615250.1 hypothetical protein -
FR830_RS05720 1160831..1161058 + 228 WP_072057801.1 DUF1272 domain-containing protein -
FR830_RS05725 1161386..1162204 + 819 WP_058655255.1 AraC family transcriptional regulator -
FR830_RS05730 1162281..1162643 + 363 WP_015370120.1 cupin domain-containing protein -
FR830_RS05735 1162843..1163379 + 537 WP_015370121.1 dihydrofolate reductase family protein -
FR830_RS05740 1163555..1164355 + 801 WP_047075865.1 nucleotidyltransferase domain-containing protein -
FR830_RS05745 1164514..1164615 - 102 Protein_1105 preprotein translocase -
FR830_RS05750 1165012..1165341 - 330 WP_151584431.1 TA system toxin CbtA family protein Toxin
FR830_RS05755 1165362..1165679 - 318 WP_151584434.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
FR830_RS05760 1165697..1165918 - 222 WP_151584437.1 DUF987 domain-containing protein -
FR830_RS05765 1165927..1166409 - 483 WP_151584440.1 RadC family protein -
FR830_RS05770 1166418..1166876 - 459 WP_151584443.1 antirestriction protein -
FR830_RS05775 1166962..1167198 - 237 WP_151584446.1 DUF905 domain-containing protein -
FR830_RS05780 1167276..1167686 - 411 WP_151584449.1 hypothetical protein -
FR830_RS05785 1167751..1168188 - 438 WP_125258379.1 hypothetical protein -
FR830_RS05790 1168230..1168766 - 537 WP_151584452.1 DUF4339 domain-containing protein -
FR830_RS05795 1168792..1169502 - 711 WP_151584455.1 DeoR family transcriptional regulator -
FR830_RS05800 1169711..1170535 - 825 WP_151584458.1 DUF945 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1159994..1188537 28543


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12271.23 Da        Isoelectric Point: 9.8189

>T135815 WP_151584431.1 NZ_CP042530:c1165341-1165012 [Klebsiella aerogenes]
MKTLPATISRATKPCLSPVAVWQMLLTRLLDQHYGLTLNDTPFSDKTVIQEYINAGVSLSDAVNFLVEKYGLARIDRKGF
SWQEQSPYLSVVDILRARRSTGLLKTDVK

Download         Length: 330 bp

>T135815 NZ_CP042530:c1165341-1165012 [Klebsiella aerogenes]
ATGAAAACTCTACCTGCTACAATTTCGCGGGCGACGAAGCCCTGTCTGTCGCCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGCCTGCTGGATCAACACTATGGCCTGACGCTAAACGACACGCCGTTCAGTGATAAAACAGTTATTCAGGAATATATTA
ATGCTGGAGTATCGCTCAGCGATGCGGTGAATTTTCTTGTCGAAAAATACGGGCTTGCCCGTATCGACCGAAAGGGATTT
TCATGGCAAGAACAGAGCCCGTATCTTTCCGTAGTGGATATTTTGCGAGCAAGACGCTCTACCGGCTTGCTAAAAACTGA
CGTGAAATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11746.37 Da        Isoelectric Point: 6.6197

>AT135815 WP_151584434.1 NZ_CP042530:c1165679-1165362 [Klebsiella aerogenes]
MSNTTWGLQRDITPCLGARLVQEGSRLHYLADRASITGKFSDAECLKLDVAFPHFISQMESMLTTGEMNPRHVHCVTLYH
NGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 318 bp

>AT135815 NZ_CP042530:c1165679-1165362 [Klebsiella aerogenes]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGTGCCTGGGAGCACGTCTGGTGCAGGAAGGCAGCCGGCT
GCACTATCTGGCTGACCGGGCAAGTATCACAGGTAAGTTTAGTGATGCCGAATGCCTGAAGTTGGATGTCGCATTCCCGC
ATTTTATCAGTCAGATGGAATCAATGCTGACTACTGGTGAAATGAACCCTCGCCATGTCCACTGTGTCACCTTGTACCAC
AACGGTTTCACCTGCGAAGCCGACACTCTTGGCAGTTGCGGCTATGTATACATCGCCGTCTATCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References