Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1903007..1903152 Replicon chromosome
Accession NZ_CP042520
Organism Klebsiella pneumoniae strain C2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1903043..1903145 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1903007..1903152 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR744_RS09490 1898137..1900197 + 2061 WP_004151449.1 oligopeptidase B -
FR744_RS09495 1900201..1900860 - 660 WP_021440386.1 exodeoxyribonuclease X -
FR744_RS09500 1900939..1901169 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FR744_RS09505 1901282..1901656 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FR744_RS09510 1901660..1902529 + 870 WP_021440385.1 copper homeostasis membrane protein CopD -
FR744_RS09515 1902546..1902884 + 339 WP_002911404.1 YebY family protein -
- 1903007..1903152 - 146 - - Antitoxin
- 1903043..1903145 + 103 - - Toxin
FR744_RS09525 1903521..1903664 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FR744_RS09530 1903769..1904737 - 969 WP_014907334.1 VirK/YbjX family protein -
FR744_RS09535 1904894..1905547 + 654 WP_021440384.1 protein-serine/threonine phosphatase -
FR744_RS09540 1905544..1905735 - 192 WP_002911395.1 YebW family protein -
FR744_RS09545 1905833..1906072 - 240 WP_002911393.1 YebV family protein -
FR744_RS09550 1906188..1907621 - 1434 WP_151641712.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T135797 NZ_CP042520:1903043-1903145 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT135797 NZ_CP042520:c1903152-1903007 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References