Detailed information of TA system TA135744

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pemIK/PRK09812-MazE
• Location: 4390810..4391400
• Replicon: chromosome
• Accession: NZ_CP042499
• Organism: Enterobacter sp. E76

Toxin (Protein)

• Gene name: pemK
• Uniprot ID: -
• Locus tag: FR762_RS21295
• Protein ID: WP_125292343.1
• Coordinates: 4390810..4391142 (-)
• Length: 111 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: -
• Locus tag: FR762_RS21300
• Protein ID: WP_125292508.1
• Coordinates: 4391143..4391400 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (1-109)

Antitoxin

• Antitoxin PemI-like (4-84)

Sequences

Toxin

Protein

• Length: 111 a.a.
• Molecular weight: 11839.66 Da
• Isoelectric Point: 10.2966

>T135744 WP_125292343.1 NZ_CP042499:c4391142-4390810 [Enterobacter sp. E76]
MDRGEIWLVSLDPTAGHEQSGKRPVLIVSKASFNTFTRLPVVVPVTSGGHFARAAGFTVSLDGAGTKTTGVIRCDQPRTI
DMVARSGKRLERIPEAIVNEVLARLEAILN

Nucleotide

• Length: 333 bp

>T135744 NZ_CP042499:c4391142-4390810 [Enterobacter sp. E76]
ATGGACAGAGGCGAAATCTGGCTCGTTTCACTTGATCCCACTGCGGGCCATGAACAAAGCGGAAAGCGTCCGGTGCTTAT
CGTATCGAAGGCATCGTTTAATACCTTTACCCGTCTGCCCGTTGTTGTTCCCGTTACCAGTGGCGGACACTTTGCCCGTG
CTGCGGGTTTTACCGTCTCACTGGACGGGGCCGGCACAAAAACAACGGGCGTCATTCGCTGTGACCAACCCAGAACCATT
GATATGGTAGCCAGGAGCGGCAAACGTCTGGAACGTATCCCCGAGGCGATAGTGAATGAAGTGCTGGCCAGGCTGGAAGC
TATTCTGAACTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9372.94 Da
• Isoelectric Point: 4.7862

>AT135744 WP_125292508.1 NZ_CP042499:c4391400-4391143 [Enterobacter sp. E76]
MYTTRLKKVGGSVMLTVPPAVLKTLGLTTDSEVGMTIDKGCLIIEAQKRPRYSLEELLAQCDPNAELSKEDREWIDAPPV
GKEIL

Nucleotide

• Length: 258 bp

>AT135744 NZ_CP042499:c4391400-4391143 [Enterobacter sp. E76]
ATGTATACCACTCGCCTAAAAAAGGTCGGAGGATCTGTGATGCTTACGGTACCTCCCGCTGTGCTTAAAACGCTGGGTCT
AACGACGGACAGTGAAGTCGGTATGACTATTGATAAGGGCTGCCTGATTATTGAGGCCCAGAAACGGCCCCGTTATTCAC
TTGAGGAATTGTTGGCGCAGTGCGATCCCAACGCTGAACTGAGCAAAGAGGATCGAGAATGGATTGATGCACCGCCGGTG
GGTAAGGAGATCCTGTAA