Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3244448..3244616 Replicon chromosome
Accession NZ_CP042499
Organism Enterobacter sp. E76

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3244508..3244612 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3244448..3244616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR762_RS15450 3240837..3241505 - 669 WP_151604506.1 exodeoxyribonuclease X -
FR762_RS15455 3241529..3242254 - 726 WP_144132604.1 carbon-nitrogen hydrolase family protein -
FR762_RS15460 3242370..3242600 - 231 WP_125291926.1 DNA polymerase III subunit theta -
FR762_RS15465 3242751..3243125 + 375 WP_144132602.1 CopC domain-containing protein YobA -
FR762_RS15470 3243127..3244002 + 876 WP_151604508.1 copper homeostasis membrane protein CopD -
FR762_RS15475 3244028..3244366 + 339 WP_125291929.1 YebY family protein -
- 3244448..3244616 - 169 - - Antitoxin
- 3244508..3244612 + 105 - - Toxin
FR762_RS15480 3244699..3245781 - 1083 WP_151604510.1 phage integrase Arm DNA-binding domain-containing protein -
FR762_RS15485 3245756..3246028 - 273 WP_151604512.1 excisionase -
FR762_RS15490 3246093..3248678 - 2586 WP_151604514.1 3'-5' exoribonuclease -
FR762_RS15495 3248819..3249157 - 339 WP_192798656.1 Rrf2 family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3147469..3319534 172065


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 105 bp

>T135736 NZ_CP042499:3244508-3244612 [Enterobacter sp. E76]
GGCAAGGCGATTTCAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATA
CAGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 169 bp

>AT135736 NZ_CP042499:c3244616-3244448 [Enterobacter sp. E76]
AGATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTGAAATCGCCTTGCCCTTTAAGAATAGATTACGATGTCAGGTTTTCCAGTCCGCGACAAAAGTGGT
CCAAAAAAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References