Detailed information of TA system TA135734

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): Hha-TomB/-
• Location: 2475538..2476159
• Replicon: chromosome
• Accession: NZ_CP042499
• Organism: Enterobacter sp. E76

Toxin (Protein)

• Gene name: Hha
• Uniprot ID: A0A3R9FT17
• Locus tag: FR762_RS11830
• Protein ID: WP_059040068.1
• Coordinates: 2475538..2475756 (-)
• Length: 73 a.a.

Antitoxin (Protein)

• Gene name: TomB
• Uniprot ID: -
• Locus tag: FR762_RS11835
• Protein ID: WP_125294098.1
• Coordinates: 2475785..2476159 (-)
• Length: 125 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Haemolysin expression modulating, HHA (13-69)

Antitoxin

• Biofilm formation regulator YbaJ (1-116)

Sequences

Toxin

Protein

• Length: 73 a.a.
• Molecular weight: 8640.05 Da
• Isoelectric Point: 8.9008

>T135734 WP_059040068.1 NZ_CP042499:c2475756-2475538 [Enterobacter sp. E76]
MSEKPLTKIDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR

Nucleotide

• Length: 219 bp

>T135734 NZ_CP042499:c2475756-2475538 [Enterobacter sp. E76]
ATGTCAGAAAAGCCTTTAACAAAAATTGATTATTTAATGCGTCTACGACGCTGTCAGACGATTGATACGCTTGAGCGGGT
AATTGAGAAAAATAAATACGAATTATCAGATAACGAACTGGCGGTATTTTATTCAGCAGCCGACCACCGTCTCGCCGAAC
TGACGATGAATAAGCTTTACGATAAAATACCGTCTTCTGTGTGGAAATTTATCCGTTAA

Antitoxin

Protein

• Length: 125 a.a.
• Molecular weight: 14341.12 Da
• Isoelectric Point: 4.6864

>AT135734 WP_125294098.1 NZ_CP042499:c2476159-2475785 [Enterobacter sp. E76]
MDEYSPKRHDIAQLKFLCENLYHDCLATLGDSNHGWVNDPTSAINLQLNELIEHIASFALNYKIKYDEDNALIEQIDEYL
DDTFMLFSNYGISAQDLQKWRKSGNRLFKCFVNVSKANPVSLSF

Nucleotide

• Length: 375 bp

>AT135734 NZ_CP042499:c2476159-2475785 [Enterobacter sp. E76]
ATGGACGAATACTCACCAAAACGGCATGATATAGCGCAGCTAAAATTCTTGTGCGAAAATCTGTATCATGACTGCCTGGC
TACGCTTGGTGATAGCAATCACGGCTGGGTCAACGATCCAACCTCGGCCATCAACCTGCAGCTAAATGAATTGATTGAGC
ATATTGCGAGTTTTGCGCTTAATTACAAAATTAAGTATGACGAAGACAATGCGTTGATTGAACAGATCGATGAATACCTC
GATGATACCTTCATGTTGTTTAGCAACTACGGGATAAGCGCCCAGGACTTACAGAAATGGCGCAAATCGGGCAATCGCCT
GTTCAAATGCTTTGTCAACGTTAGTAAGGCCAACCCAGTGAGCCTTTCTTTTTAA

Structures

Toxin

• AlphaFold DB: A0A3R9FT17