Detailed information of TA system TA135732

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2299034..2299561
• Replicon: chromosome
• Accession: NZ_CP042499
• Organism: Enterobacter sp. E76

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FR762_RS11015
• Protein ID: WP_151603695.1
• Coordinates: 2299286..2299561 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FR762_RS11010
• Protein ID: WP_151605614.1
• Coordinates: 2299034..2299282 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-44)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 11016.37 Da
• Isoelectric Point: 5.5494

>T135732 WP_151603695.1 NZ_CP042499:2299286-2299561 [Enterobacter sp. E76]
MEIYWTHKAQDDLARIYRFAFQYSRQHATEVVDRLIASSADLTQHPAIGIQQTRYLPREVRKVLFDDYEIHYQIVENDIF
VLDLWSTREDR

Nucleotide

• Length: 276 bp

>T135732 NZ_CP042499:2299286-2299561 [Enterobacter sp. E76]
ATGGAAATTTACTGGACGCATAAAGCTCAGGATGATCTGGCGCGGATTTATCGGTTTGCCTTTCAATATAGCCGCCAGCA
TGCAACAGAAGTCGTAGACCGGTTAATCGCTTCAAGCGCTGACCTTACCCAACATCCAGCAATCGGCATCCAGCAAACGC
GCTATCTTCCCAGGGAAGTAAGGAAGGTCTTGTTTGATGATTATGAAATTCATTATCAAATTGTGGAGAACGATATTTTT
GTACTCGATCTCTGGAGCACCAGAGAGGACAGGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9124.43 Da
• Isoelectric Point: 5.6882

>AT135732 WP_151605614.1 NZ_CP042499:2299034-2299282 [Enterobacter sp. E76]
MGSSTKQTISAQIPVELATAVEQLALELDRSKSWIIKEALTAMLAERERRHQSIQAGLDDVTEGRVISHAEMMNFASQLK
KE

Nucleotide

• Length: 249 bp

>AT135732 NZ_CP042499:2299034-2299282 [Enterobacter sp. E76]
ATGGGTTCTTCAACCAAACAGACCATTAGCGCGCAAATTCCGGTGGAACTCGCTACTGCCGTTGAGCAGTTGGCACTTGA
ACTGGATCGGTCAAAAAGCTGGATTATCAAAGAAGCGCTTACTGCCATGCTGGCTGAAAGGGAGCGTCGGCATCAGAGCA
TTCAGGCGGGACTGGATGATGTTACTGAGGGCAGAGTGATTAGCCACGCAGAGATGATGAATTTTGCCAGTCAGTTGAAG
AAAGAGTAA