Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 319247..319913 Replicon chromosome
Accession NZ_CP042499
Organism Enterobacter sp. E76

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FR762_RS01440 Protein ID WP_151602299.1
Coordinates 319247..319666 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FR762_RS01445 Protein ID WP_125295342.1
Coordinates 319647..319913 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR762_RS01420 315244..316977 - 1734 WP_125295338.1 single-stranded-DNA-specific exonuclease RecJ -
FR762_RS01425 316981..317694 - 714 WP_125295339.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FR762_RS01430 317720..318619 - 900 WP_125295350.1 site-specific tyrosine recombinase XerD -
FR762_RS01435 318721..319242 + 522 WP_125295340.1 flavodoxin FldB -
FR762_RS01440 319247..319666 - 420 WP_151602299.1 protein YgfX Toxin
FR762_RS01445 319647..319913 - 267 WP_125295342.1 FAD assembly factor SdhE Antitoxin
FR762_RS01450 320172..321158 + 987 WP_151602301.1 tRNA-modifying protein YgfZ -
FR762_RS01455 321193..321852 - 660 WP_125295344.1 hemolysin III family protein -
FR762_RS01460 321982..322293 - 312 WP_151602304.1 N(4)-acetylcytidine aminohydrolase -
FR762_RS01465 322407..323144 + 738 WP_192798679.1 MurR/RpiR family transcriptional regulator -
FR762_RS01470 323268..324701 + 1434 WP_151602307.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16352.25 Da        Isoelectric Point: 11.0916

>T135728 WP_151602299.1 NZ_CP042499:c319666-319247 [Enterobacter sp. E76]
VVLWQSDLRVSWRAQWFSLMLHGIVAAVILLLPWPLSYMPVWLVLLSLVVFDCVRSQRRIHSLQGEVKLTMDYRLRWQGV
EWELIGAPWMLQSGMLLRLRHPGTQRSQHLWLAADSMDASEWRDLRRVLLQQPQSGRPS

Download         Length: 420 bp

>T135728 NZ_CP042499:c319666-319247 [Enterobacter sp. E76]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCGTGGCGCGCACAGTGGTTTTCCCTCATGCTGCACGGCATTGTCGCAGC
GGTGATCTTACTGCTGCCCTGGCCGCTGAGTTATATGCCGGTTTGGTTGGTTTTACTGTCGCTGGTGGTGTTTGATTGCG
TGCGCAGCCAGCGGCGTATTCATTCGCTGCAGGGCGAGGTAAAACTGACGATGGATTATCGGCTGCGCTGGCAGGGTGTG
GAATGGGAGCTGATAGGCGCGCCGTGGATGCTGCAAAGCGGTATGCTGCTGCGCTTGCGGCATCCAGGCACTCAACGCAG
CCAGCATTTATGGCTGGCGGCGGACAGCATGGATGCCAGTGAATGGCGCGATTTGCGCCGGGTGTTGTTACAGCAACCGC
AAAGCGGCCGCCCGTCATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10491.99 Da        Isoelectric Point: 5.5535

>AT135728 WP_125295342.1 NZ_CP042499:c319913-319647 [Enterobacter sp. E76]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDALSDDDKHVFIRLLECDDPDLFNWLMNHGKPADPELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT135728 NZ_CP042499:c319913-319647 [Enterobacter sp. E76]
ATGGATATTAACAATAAAGCCCGTATTCACTGGGCGTGCCGTCGCGGGATGCGTGAGCTGGATATCTCTATCATGCCGTT
CTTTGAACACGAGTACGACGCTCTGAGCGATGACGATAAACACGTGTTTATTCGCCTGCTCGAATGCGACGACCCCGATC
TTTTTAACTGGTTAATGAATCACGGTAAGCCTGCGGACCCTGAGCTGCAGCGCATGGTGCAACTGATTCAGACGCGGAAC
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References