Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3687237..3687381 | Replicon | chromosome |
| Accession | NZ_CP042481 | ||
| Organism | Klebsiella pneumoniae strain C51 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3687243..3687345 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3687237..3687381 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FR751_RS18070 | 3682913..3684040 | - | 1128 | WP_064147220.1 | hypothetical protein | - |
| FR751_RS18075 | 3684155..3685123 | - | 969 | WP_080923262.1 | IS5-like element IS903B family transposase | - |
| FR751_RS28690 | 3685125..3685484 | - | 360 | WP_192796496.1 | hypothetical protein | - |
| FR751_RS18085 | 3686273..3686752 | - | 480 | WP_032419797.1 | lysis protein | - |
| FR751_RS18090 | 3686751..3687110 | + | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| - | 3687237..3687381 | + | 145 | - | - | Antitoxin |
| - | 3687243..3687345 | - | 103 | - | - | Toxin |
| FR751_RS18095 | 3687504..3687842 | - | 339 | WP_002911404.1 | YebY family protein | - |
| FR751_RS18100 | 3687859..3688728 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| FR751_RS18105 | 3688732..3689106 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| FR751_RS18110 | 3689219..3689449 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| FR751_RS18115 | 3689528..3690187 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| FR751_RS18120 | 3690191..3692251 | - | 2061 | WP_151675887.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3671387..3707982 | 36595 | |
| - | flank | IS/Tn | - | - | 3684155..3685123 | 968 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T135691 NZ_CP042481:c3687345-3687243 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT135691 NZ_CP042481:3687237-3687381 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
