Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2167848..2167990 Replicon chromosome
Accession NZ_CP042478
Organism Citrobacter freundii strain C50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2167883..2167986 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2167848..2167990 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FR753_RS10620 2164020..2164406 + 387 WP_151532620.1 hypothetical protein -
FR753_RS10625 2164569..2164922 - 354 WP_137397182.1 hypothetical protein -
FR753_RS10630 2165216..2165461 - 246 WP_115454751.1 hypothetical protein -
FR753_RS10640 2166118..2166492 + 375 WP_003034928.1 CopC domain-containing protein YobA -
FR753_RS10645 2166496..2167368 + 873 WP_032935389.1 copper homeostasis membrane protein CopD -
FR753_RS10650 2167389..2167727 + 339 WP_003034934.1 YebY family protein -
- 2167848..2167990 - 143 - - Antitoxin
- 2167883..2167986 + 104 - - Toxin
FR753_RS10655 2168064..2169149 - 1086 WP_001129310.1 phage integrase Arm DNA-binding domain-containing protein -
FR753_RS10660 2169118..2169390 - 273 WP_151532621.1 excisionase -
FR753_RS10665 2169454..2169696 - 243 WP_001237028.1 DUF4060 family protein -
FR753_RS10670 2169683..2170390 - 708 WP_151532622.1 hypothetical protein -
FR753_RS10675 2170383..2170727 - 345 WP_151532623.1 hypothetical protein -
FR753_RS10680 2170762..2171847 - 1086 WP_151532624.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2157679..2216034 58355


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T135668 NZ_CP042478:2167883-2167986 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 143 bp

>AT135668 NZ_CP042478:c2167990-2167848 [Citrobacter freundii]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References