135662

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 5515303..5516488 Replicon chromosome
Accession NZ_CP042467
Organism Microvenator marinus strain V1718

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag FRD01_RS22660 Protein ID WP_146963262.1
Coordinates 5515940..5516488 (+) Length 183 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag FRD01_RS22655 Protein ID WP_146963260.1
Coordinates 5515303..5515899 (+) Length 199 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRD01_RS22640 (FRD01_22640) 5510495..5510677 + 183 WP_146963254.1 hypothetical protein -
FRD01_RS22645 (FRD01_22645) 5510838..5511788 + 951 WP_249755836.1 Abi family protein -
FRD01_RS22650 (FRD01_22650) 5512085..5515033 - 2949 WP_146963258.1 fibrinogen-like YCDxxxxGGGW domain-containing protein -
FRD01_RS22655 (FRD01_22655) 5515303..5515899 + 597 WP_146963260.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
FRD01_RS22660 (FRD01_22660) 5515940..5516488 + 549 WP_146963262.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FRD01_RS22665 (FRD01_22665) 5516552..5516881 + 330 WP_146963264.1 VF530 family protein -
FRD01_RS22670 (FRD01_22670) 5516878..5517207 + 330 WP_146963266.1 hypothetical protein -
FRD01_RS24535 5517204..5517371 + 168 WP_249755837.1 hypothetical protein -
FRD01_RS22675 (FRD01_22675) 5517376..5517858 - 483 WP_146963268.1 hypothetical protein -
FRD01_RS22680 (FRD01_22680) 5518052..5518651 + 600 WP_146963270.1 hypothetical protein -
FRD01_RS22685 (FRD01_22685) 5518626..5519078 - 453 WP_146963272.1 EVE domain-containing protein -
FRD01_RS24770 5519188..5519313 + 126 WP_283808674.1 hypothetical protein -
FRD01_RS22690 (FRD01_22690) 5519570..5520706 - 1137 WP_146963274.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(5-128)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-51)


Sequences

Toxin        


Download         Length: 183 a.a.        Molecular weight: 20405.64 Da        Isoelectric Point: 5.7954

>T135662 WP_146963262.1 NZ_CP042467:5515940-5516488 [Microvenator marinus]
MLHNAKIPIQIDIGFGDAVTPALDQIEYPTLLDGQPPKLKAYPRYTVVAEKVEAMVKLGLANSRMKDFYDVWLLSKLFTF
DGQLLALAFKNTFERRSTTLPLTMPTALSPSFTEGSQKLVQWNAFIRKAKSKIDVPELSVVAEEIAAFVMPVFDSLGMET
TFEQAWTSGDGWKRSILATEHF

Download         Length: 549 bp

>T135662 NZ_CP042467:5515940-5516488 [Microvenator marinus]
TTGCTACACAATGCAAAGATTCCGATTCAGATCGATATTGGCTTTGGCGACGCAGTAACCCCCGCTCTTGATCAAATTGA
GTATCCGACATTGCTGGATGGACAACCTCCCAAACTAAAAGCTTACCCTCGATACACGGTGGTAGCCGAAAAAGTGGAGG
CGATGGTTAAACTCGGCTTGGCGAACAGTAGGATGAAGGACTTTTACGATGTTTGGCTTCTTTCGAAGTTGTTTACTTTC
GATGGTCAGCTTCTTGCACTGGCTTTCAAAAACACCTTTGAGCGTCGATCAACAACTCTGCCTCTCACAATGCCCACTGC
TTTGTCTCCGTCATTCACCGAGGGTTCGCAGAAGTTGGTCCAGTGGAACGCATTTATCAGGAAGGCCAAATCAAAAATCG
ATGTTCCAGAGTTGTCCGTGGTTGCCGAAGAGATTGCGGCATTCGTGATGCCTGTCTTTGATAGCCTGGGAATGGAGACT
ACTTTTGAACAGGCCTGGACTTCTGGCGACGGATGGAAAAGGTCCATTCTTGCAACCGAACACTTCTAA

Antitoxin


Download         Length: 199 a.a.        Molecular weight: 22136.23 Da        Isoelectric Point: 5.5996

>AT135662 WP_146963260.1 NZ_CP042467:5515303-5515899 [Microvenator marinus]
MRHYDKITELAANKGIISASDVEELGISRNYLYAMCREGLLERSSRGLYMLADSDVSAHHGLAEISKRIPSSVISLISAL
NFHELTTQIPHEVWFSIPRDTWLPEIDYPPIQVTRVSEPAYSFGVEEHTIGGVSVSIYSPAKTVADCFKFRSKVGLDVAI
EALRSAWDARKITVDELVQAAQVDRVWTVIRPYVEATV

Download         Length: 597 bp

>AT135662 NZ_CP042467:5515303-5515899 [Microvenator marinus]
ATGAGACACTACGACAAGATAACCGAACTGGCGGCAAACAAGGGAATCATCAGCGCCAGCGATGTTGAAGAGCTGGGGAT
CTCACGCAACTACCTTTACGCAATGTGCCGCGAAGGACTGCTCGAGAGGAGCTCGCGAGGGCTATATATGCTTGCTGACT
CGGACGTGAGCGCACACCACGGTCTTGCTGAGATTTCAAAAAGAATTCCCAGCTCCGTAATCTCACTCATATCCGCTCTT
AACTTCCACGAACTCACCACCCAAATCCCGCACGAGGTCTGGTTCTCCATTCCTCGAGACACGTGGCTGCCTGAGATAGA
CTATCCGCCTATTCAAGTCACAAGAGTTTCAGAGCCTGCCTACTCGTTTGGTGTAGAAGAACATACCATTGGAGGTGTGA
GCGTAAGCATCTACTCCCCAGCAAAGACAGTCGCGGATTGTTTTAAATTTCGGAGCAAGGTTGGACTTGATGTGGCTATT
GAGGCTCTTCGTTCCGCTTGGGATGCTCGGAAAATCACGGTGGATGAACTTGTCCAAGCCGCTCAAGTCGACCGGGTCTG
GACGGTGATTCGCCCCTACGTGGAGGCAACGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References