Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 1523985..1524532 | Replicon | chromosome |
| Accession | NZ_CP042449 | ||
| Organism | Vibrio alginolyticus strain FA2 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A347UR19 |
| Locus tag | FR729_RS06715 | Protein ID | WP_025548916.1 |
| Coordinates | 1523985..1524287 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | FR729_RS06720 | Protein ID | WP_167415260.1 |
| Coordinates | 1524275..1524532 (-) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FR729_RS06680 | 1519622..1519963 | - | 342 | WP_017821457.1 | RDD family protein | - |
| FR729_RS06685 | 1520177..1520785 | - | 609 | WP_005389306.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| FR729_RS06690 | 1520929..1521330 | - | 402 | WP_137282082.1 | DUF2007 domain-containing protein | - |
| FR729_RS06695 | 1521529..1522104 | - | 576 | WP_132937086.1 | hypothetical protein | - |
| FR729_RS06700 | 1522149..1522241 | - | 93 | WP_132937085.1 | DUF3265 domain-containing protein | - |
| FR729_RS06705 | 1522879..1523808 | - | 930 | WP_167415259.1 | hypothetical protein | - |
| FR729_RS06710 | 1523857..1523988 | - | 132 | WP_167415685.1 | DUF3265 domain-containing protein | - |
| FR729_RS06715 | 1523985..1524287 | - | 303 | WP_025548916.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FR729_RS06720 | 1524275..1524532 | - | 258 | WP_167415260.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| FR729_RS24060 | 1524614..1524706 | - | 93 | WP_079380089.1 | DUF3265 domain-containing protein | - |
| FR729_RS06730 | 1524732..1525199 | - | 468 | WP_062866184.1 | cold shock domain-containing protein | - |
| FR729_RS06735 | 1525238..1525327 | - | 90 | WP_079767000.1 | DUF3265 domain-containing protein | - |
| FR729_RS06740 | 1525345..1525623 | - | 279 | WP_020840791.1 | hypothetical protein | - |
| FR729_RS06745 | 1525823..1526305 | - | 483 | WP_167415261.1 | DUF2007 domain-containing protein | - |
| FR729_RS06750 | 1526350..1526442 | - | 93 | WP_080252672.1 | DUF3265 domain-containing protein | - |
| FR729_RS06755 | 1526465..1527370 | - | 906 | WP_167415262.1 | immunity 49 family protein | - |
| FR729_RS06760 | 1528143..1528691 | - | 549 | WP_025502382.1 | hypothetical protein | - |
| FR729_RS06765 | 1528732..1528821 | - | 90 | WP_077345960.1 | DUF3265 domain-containing protein | - |
| FR729_RS06770 | 1528839..1529252 | - | 414 | WP_167415263.1 | hypothetical protein | - |
| FR729_RS06775 | 1529333..1529425 | - | 93 | WP_079858460.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1514574..1605716 | 91142 | |
| - | inside | Integron | - | - | 1522757..1604598 | 81841 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11669.57 Da Isoelectric Point: 5.1765
>T135653 WP_025548916.1 NZ_CP042449:c1524287-1523985 [Vibrio alginolyticus]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLSKQ
Download Length: 303 bp
>T135653 NZ_CP042449:c1524287-1523985 [Vibrio alginolyticus]
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTTGAACGCCTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGAGTAAGCAATAA
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTTGAACGCCTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGAGTAAGCAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9495.01 Da Isoelectric Point: 6.7178
>AT135653 WP_167415260.1 NZ_CP042449:c1524532-1524275 [Vibrio alginolyticus]
MKVELVTSLKCQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKGKM
SKWLK
MKVELVTSLKCQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKGKM
SKWLK
Download Length: 258 bp
>AT135653 NZ_CP042449:c1524532-1524275 [Vibrio alginolyticus]
ATGAAAGTAGAACTAGTTACATCACTCAAATGTCAAGCAACTAAGATCCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGGCAAAATG
TCAAAATGGCTGAAATAA
ATGAAAGTAGAACTAGTTACATCACTCAAATGTCAAGCAACTAAGATCCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACGGTAAAGTGGTAAGTCATGATGAAGCCAAGGGCAAAATG
TCAAAATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|