Detailed information of TA system TA135652

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 3564618..3565123
• Replicon: chromosome
• Accession: NZ_CP042437
• Organism: Mucilaginibacter ginsenosidivorax strain KHI28

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FSB76_RS14935
• Protein ID: WP_147054631.1
• Coordinates: 3564869..3565123 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: FSB76_RS14930
• Protein ID: WP_147054629.1
• Coordinates: 3564618..3564872 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSB76_RS14915	3559786..3560553	+	768	WP_147060988.1	lytic transglycosylase domain-containing protein	-
FSB76_RS14920	3560950..3563796	+	2847	WP_147054625.1	excinuclease ABC subunit UvrA	-
FSB76_RS14925	3563837..3564568	+	732	WP_147054627.1	phosphodiester glycosidase family protein	-
FSB76_RS14930	3564618..3564872	+	255	WP_147054629.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FSB76_RS14935	3564869..3565123	+	255	WP_147054631.1	Txe/YoeB family addiction module toxin	Toxin
FSB76_RS14940	3565120..3565686	-	567	WP_147054633.1	RNA polymerase sigma-70 factor	-
FSB76_RS14945	3565930..3566991	+	1062	WP_147054635.1	DUF4974 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9964.32 Da
• Isoelectric Point: 7.9417

>T135652 WP_147054631.1 NZ_CP042437:3564869-3565123 [Mucilaginibacter ginsenosidivorax]
VRIGFSDQAWEDYLYWQTTDKSILRKINALVKDIERTPFEGSGKPEPLKHNLAGLWCRRINLEHCLVYKIDNGSIHIHQS
HYHY

Nucleotide

• Length: 255 bp

>T135652 NZ_CP042437:3564869-3565123 [Mucilaginibacter ginsenosidivorax]
GTGAGAATCGGTTTTTCCGATCAGGCCTGGGAAGATTATCTATATTGGCAGACTACCGATAAATCCATTTTAAGAAAAAT
AAATGCTTTAGTAAAAGATATAGAAAGAACTCCATTTGAAGGTTCTGGCAAACCAGAGCCGTTAAAGCATAATTTAGCGG
GTTTGTGGTGTCGACGGATAAATTTAGAACATTGCCTTGTATACAAAATTGACAACGGATCAATTCATATCCATCAATCC
CACTATCATTACTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9747.08 Da
• Isoelectric Point: 4.8605

>AT135652 WP_147054629.1 NZ_CP042437:3564618-3564872 [Mucilaginibacter ginsenosidivorax]
MEVTTYTTFRQQLKFYLDKVRNDHKPLVVKSTNAEDVVVISKADYESMEETFYLLKSPANSARLMKSIEDLENGLGTERK
LIEE

Nucleotide

• Length: 255 bp

>AT135652 NZ_CP042437:3564618-3564872 [Mucilaginibacter ginsenosidivorax]
ATGGAAGTTACCACATATACAACCTTCAGGCAACAACTTAAATTCTATCTGGATAAAGTTCGCAATGATCATAAACCCTT
AGTGGTTAAAAGTACGAATGCAGAGGATGTTGTAGTTATTTCTAAAGCTGATTATGAAAGCATGGAAGAAACATTTTACT
TGCTTAAAAGTCCTGCAAATTCTGCCCGGCTGATGAAAAGCATAGAGGATTTGGAAAATGGTTTAGGTACCGAAAGAAAA
CTGATTGAAGAGTGA