Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 265078..265640 Replicon chromosome
Accession NZ_CP042436
Organism Mucilaginibacter ginsenosidivorans strain Gsoil 3017

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FRZ54_RS01200 Protein ID WP_147029830.1
Coordinates 265299..265640 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FRZ54_RS01195 Protein ID WP_147029829.1
Coordinates 265078..265302 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRZ54_RS01190 261591..264917 + 3327 WP_147029828.1 vitamin B12-dependent ribonucleotide reductase -
FRZ54_RS01195 265078..265302 + 225 WP_147029829.1 DUF433 domain-containing protein Antitoxin
FRZ54_RS01200 265299..265640 + 342 WP_147029830.1 DUF5615 family PIN-like protein Toxin
FRZ54_RS01205 265743..266264 + 522 WP_147029831.1 DinB family protein -
FRZ54_RS01210 266402..266926 + 525 WP_147029832.1 DinB family protein -
FRZ54_RS01215 267003..267434 - 432 WP_147029833.1 hypothetical protein -
FRZ54_RS01220 267495..267905 - 411 WP_147029834.1 hypothetical protein -
FRZ54_RS01225 267964..269649 - 1686 WP_147029835.1 energy transducer TonB -
FRZ54_RS01230 269661..270032 - 372 WP_147029836.1 BlaI/MecI/CopY family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-79)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12586.54 Da        Isoelectric Point: 5.0187

>T135651 WP_147029830.1 NZ_CP042436:265299-265640 [Mucilaginibacter ginsenosidivorans]
MTIWINAQISPFIALWINSNFPNLSAQSLRSLGLRDAKDDEVFQEARKANVTLMSKDQDFVRLIGLHGIPPKLIWITCGN
TSNAALCEILYTALPKAVEMLNSNENVVEISNL

Download         Length: 342 bp

>T135651 NZ_CP042436:265299-265640 [Mucilaginibacter ginsenosidivorans]
ATGACCATTTGGATCAATGCCCAAATATCCCCGTTTATCGCTCTGTGGATAAATAGCAATTTCCCAAACCTCAGCGCTCA
ATCCTTACGTTCTTTGGGCTTAAGAGATGCCAAAGATGATGAGGTATTTCAGGAAGCGCGCAAAGCGAATGTAACTCTTA
TGAGTAAAGACCAGGATTTTGTCAGGCTGATCGGCCTACACGGAATTCCGCCGAAACTAATATGGATAACATGTGGTAAT
ACTTCAAATGCTGCGTTGTGTGAAATACTATACACAGCGCTTCCAAAGGCGGTCGAAATGCTAAATAGTAATGAAAATGT
TGTGGAGATCAGCAATCTTTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8076.31 Da        Isoelectric Point: 4.5025

>AT135651 WP_147029829.1 NZ_CP042436:265078-265302 [Mucilaginibacter ginsenosidivorans]
MSNWKERITTDPGQCGGRPCIRGMRIRVADILDLLAAGLTQEQVLEELPDLEALDIEAALKYASSKLDHAIIAA

Download         Length: 225 bp

>AT135651 NZ_CP042436:265078-265302 [Mucilaginibacter ginsenosidivorans]
ATGAGCAATTGGAAAGAACGAATTACCACTGATCCCGGGCAATGTGGTGGCAGACCGTGTATAAGAGGAATGAGGATACG
TGTGGCTGATATTCTTGACTTGCTTGCGGCAGGCTTAACCCAGGAGCAAGTACTTGAAGAATTACCGGATCTTGAAGCCC
TGGACATCGAAGCAGCATTAAAATATGCCAGCAGTAAACTTGACCACGCCATAATTGCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References