Detailed information of TA system TA135650

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1131676..1132081
• Replicon: chromosome
• Accession: NZ_CP042429
• Organism: Corynebacterium nuruki S6-4

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FSW06_RS05095
• Protein ID: WP_083827094.1
• Coordinates: 1131676..1131855 (+)
• Length: 60 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FSW06_RS05100
• Protein ID: WP_010121657.1
• Coordinates: 1131842..1132081 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSW06_RS05065	1127673..1128053	+	381	WP_010121650.1	hypothetical protein	-
FSW06_RS05070	1128084..1128989	+	906	WP_010121651.1	hypothetical protein	-
FSW06_RS05075	1129000..1129293	-	294	WP_040430618.1	ribbon-helix-helix domain-containing protein	-
FSW06_RS05080	1129296..1129667	-	372	WP_139024551.1	hypothetical protein	-
FSW06_RS05085	1129871..1130164	+	294	WP_010121654.1	hypothetical protein	-
FSW06_RS05090	1130222..1131415	+	1194	WP_010121655.1	hypothetical protein	-
FSW06_RS05095	1131676..1131855	+	180	WP_083827094.1	BrnT family toxin	Toxin
FSW06_RS05100	1131842..1132081	+	240	WP_010121657.1	hypothetical protein	Antitoxin
FSW06_RS05105	1132131..1132322	-	192	WP_139024552.1	hypothetical protein	-
FSW06_RS14460	1132351..1132509	-	159	WP_010121659.1	alpha/beta fold hydrolase	-
FSW06_RS05115	1132445..1132843	+	399	WP_083827096.1	cation:dicarboxylase symporter family transporter	-
FSW06_RS05120	1132940..1133890	-	951	WP_010121661.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (2-52)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 7252.35 Da
• Isoelectric Point: 11.5530

>T135650 WP_083827094.1 NZ_CP042429:1131676-1131855 [Corynebacterium nuruki S6-4]
MDRHRLEVRARTLDEPRWLLIARPNQRIWSAVITYRPDHVRIISVRRARQKETALYEDQ

Nucleotide

• Length: 180 bp

>T135650 NZ_CP042429:1131676-1131855 [Corynebacterium nuruki S6-4]
CTGGACCGGCACCGCCTCGAAGTCCGGGCCCGGACCCTGGACGAACCCCGTTGGCTGCTGATCGCGCGGCCCAACCAGAG
AATCTGGTCCGCGGTGATCACCTACCGGCCTGACCATGTCCGCATCATCTCGGTACGACGAGCAAGGCAGAAGGAGACCG
CTCTCTATGAAGACCAGTAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9097.26 Da
• Isoelectric Point: 7.0157

>AT135650 WP_010121657.1 NZ_CP042429:1131842-1132081 [Corynebacterium nuruki S6-4]
MKTSRDFDRTFDEGGDVVGDLDLSTARRPGEEQKRVNVDFPVWMVTALDAEARHLGVTRQSIIKLWLAERLEQRRRPAS

Nucleotide

• Length: 240 bp

>AT135650 NZ_CP042429:1131842-1132081 [Corynebacterium nuruki S6-4]
ATGAAGACCAGTAGAGACTTCGACCGGACATTCGACGAAGGTGGCGACGTCGTCGGCGACCTCGATCTCAGCACAGCGCG
GCGCCCCGGTGAGGAGCAGAAGCGGGTCAACGTCGATTTCCCCGTATGGATGGTCACCGCACTTGACGCGGAGGCACGTC
ATCTCGGGGTCACCCGACAGTCGATCATCAAGCTCTGGCTCGCCGAGCGCCTTGAGCAGCGCCGGCGCCCCGCGTCCTGA