Detailed information of TA system TA135647

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 3696184..3696731
• Replicon: chromosome
• Accession: NZ_CP042382
• Organism: Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FGL86_RS17440
• Protein ID: WP_147185949.1
• Coordinates: 3696184..3696486 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FGL86_RS17445
• Protein ID: WP_147185950.1
• Coordinates: 3696474..3696731 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGL86_RS17425	3692534..3693523	+	990	WP_186764442.1	dipeptidase	-
FGL86_RS17430	3693539..3695284	+	1746	WP_147185947.1	hypothetical protein	-
FGL86_RS17435	3695281..3696048	+	768	WP_147185948.1	DUF3726 domain-containing protein	-
FGL86_RS17440	3696184..3696486	-	303	WP_147185949.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FGL86_RS17445	3696474..3696731	-	258	WP_147185950.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
FGL86_RS17450	3696985..3698568	-	1584	WP_147185951.1	transposase	-
FGL86_RS17455	3698695..3699399	-	705	WP_147185952.1	hypothetical protein	-
FGL86_RS17460	3699578..3700897	-	1320	WP_147182695.1	IS1380 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11709.33 Da
• Isoelectric Point: 4.2444

>T135647 WP_147185949.1 NZ_CP042382:c3696486-3696184 [Pistricoccus aurantiacus]
VAEITWTELALQELDALAEYIALDNPEAASHLVEEVFDKVERLENFPQSGRVPPELPNSVYREVVVPPCRIFYREDDKRV
LILYVMREERQLRAYMLESS

Nucleotide

• Length: 303 bp

>T135647 NZ_CP042382:c3696486-3696184 [Pistricoccus aurantiacus]
GTGGCTGAAATAACCTGGACGGAGCTAGCCCTTCAGGAACTGGATGCTCTCGCTGAGTATATTGCGTTGGATAATCCTGA
GGCGGCCAGCCATTTGGTCGAAGAAGTGTTTGATAAAGTTGAGCGTCTGGAGAATTTTCCCCAATCTGGACGGGTTCCTC
CAGAACTGCCCAATTCCGTATACAGGGAAGTGGTAGTGCCTCCGTGTCGCATTTTTTATCGTGAAGATGATAAGCGGGTT
CTTATCCTATATGTCATGCGAGAGGAGCGGCAGCTTCGCGCTTACATGCTGGAGAGCAGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9857.39 Da
• Isoelectric Point: 8.5042

>AT135647 WP_147185950.1 NZ_CP042382:c3696731-3696474 [Pistricoccus aurantiacus]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGQPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
GKWLK

Nucleotide

• Length: 258 bp

>AT135647 NZ_CP042382:c3696731-3696474 [Pistricoccus aurantiacus]
ATGAAAGTTGAGCTTGTTACAAACCTTAAGCGCCAAGCTACAAAAATCTTGGCAGACCTGCATCTGTCTAAAGAGCCGGT
ACTGATCACTGAACATGGCCAGCCATCGGCTTATCTTGTTGATGTGCAGGATTACGAGTTCATGCAGCGTCGGCTTGAGC
TGCTTGAGGGGCTCTCACGGGGAGAGCGCGCTGTACTTGAGGGAAGAACGTACAGCCAAAGTGAGGCTAGGGAGAAAATG
GGTAAGTGGCTGAAATAA