Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3696184..3696731 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FGL86_RS17440 Protein ID WP_147185949.1
Coordinates 3696184..3696486 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL86_RS17445 Protein ID WP_147185950.1
Coordinates 3696474..3696731 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS17425 3692534..3693523 + 990 WP_186764442.1 dipeptidase -
FGL86_RS17430 3693539..3695284 + 1746 WP_147185947.1 hypothetical protein -
FGL86_RS17435 3695281..3696048 + 768 WP_147185948.1 DUF3726 domain-containing protein -
FGL86_RS17440 3696184..3696486 - 303 WP_147185949.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL86_RS17445 3696474..3696731 - 258 WP_147185950.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FGL86_RS17450 3696985..3698568 - 1584 WP_147185951.1 transposase -
FGL86_RS17455 3698695..3699399 - 705 WP_147185952.1 hypothetical protein -
FGL86_RS17460 3699578..3700897 - 1320 WP_147182695.1 IS1380 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11709.33 Da        Isoelectric Point: 4.2444

>T135647 WP_147185949.1 NZ_CP042382:c3696486-3696184 [Pistricoccus aurantiacus]
VAEITWTELALQELDALAEYIALDNPEAASHLVEEVFDKVERLENFPQSGRVPPELPNSVYREVVVPPCRIFYREDDKRV
LILYVMREERQLRAYMLESS

Download         Length: 303 bp

>T135647 NZ_CP042382:c3696486-3696184 [Pistricoccus aurantiacus]
GTGGCTGAAATAACCTGGACGGAGCTAGCCCTTCAGGAACTGGATGCTCTCGCTGAGTATATTGCGTTGGATAATCCTGA
GGCGGCCAGCCATTTGGTCGAAGAAGTGTTTGATAAAGTTGAGCGTCTGGAGAATTTTCCCCAATCTGGACGGGTTCCTC
CAGAACTGCCCAATTCCGTATACAGGGAAGTGGTAGTGCCTCCGTGTCGCATTTTTTATCGTGAAGATGATAAGCGGGTT
CTTATCCTATATGTCATGCGAGAGGAGCGGCAGCTTCGCGCTTACATGCTGGAGAGCAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9857.39 Da        Isoelectric Point: 8.5042

>AT135647 WP_147185950.1 NZ_CP042382:c3696731-3696474 [Pistricoccus aurantiacus]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGQPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
GKWLK

Download         Length: 258 bp

>AT135647 NZ_CP042382:c3696731-3696474 [Pistricoccus aurantiacus]
ATGAAAGTTGAGCTTGTTACAAACCTTAAGCGCCAAGCTACAAAAATCTTGGCAGACCTGCATCTGTCTAAAGAGCCGGT
ACTGATCACTGAACATGGCCAGCCATCGGCTTATCTTGTTGATGTGCAGGATTACGAGTTCATGCAGCGTCGGCTTGAGC
TGCTTGAGGGGCTCTCACGGGGAGAGCGCGCTGTACTTGAGGGAAGAACGTACAGCCAAAGTGAGGCTAGGGAGAAAATG
GGTAAGTGGCTGAAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References