Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 3513855..3514384 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag FGL86_RS16605 Protein ID WP_147185806.1
Coordinates 3513855..3514127 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL86_RS16610 Protein ID WP_147185807.1
Coordinates 3514127..3514384 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS16580 3509204..3510847 + 1644 WP_186764430.1 antiporter -
FGL86_RS16585 3511060..3512415 + 1356 WP_147185802.1 NarK/NasA family nitrate transporter -
FGL86_RS16590 3512478..3512795 - 318 WP_147185803.1 carboxymuconolactone decarboxylase family protein -
FGL86_RS16595 3512852..3513235 - 384 WP_147185804.1 SirB2 family protein -
FGL86_RS16600 3513354..3513824 + 471 WP_147185805.1 hypothetical protein -
FGL86_RS16605 3513855..3514127 - 273 WP_147185806.1 type II toxin-antitoxin system YafQ family toxin Toxin
FGL86_RS16610 3514127..3514384 - 258 WP_147185807.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FGL86_RS16615 3514461..3515684 - 1224 WP_147185808.1 NnrS family protein -
FGL86_RS16620 3515712..3516893 - 1182 WP_147185809.1 NO-inducible flavohemoprotein -
FGL86_RS16625 3517084..3518151 - 1068 WP_186764431.1 metal-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10728.43 Da        Isoelectric Point: 10.5148

>T135646 WP_147185806.1 NZ_CP042382:c3514127-3513855 [Pistricoccus aurantiacus]
MLVPVRSSQFKRDVKRVKKRNKDMTKLRRLLGLLIEQKPLPETYLDHPLRGNWKSYRDAHIEPDWLLIYRIEGNESQLAR
TGTHADLFTE

Download         Length: 273 bp

>T135646 NZ_CP042382:c3514127-3513855 [Pistricoccus aurantiacus]
ATGCTGGTGCCGGTTCGCTCCAGCCAATTCAAGCGTGACGTGAAGCGCGTTAAAAAGCGCAACAAGGACATGACCAAGTT
ACGCCGATTGCTTGGGTTGCTGATCGAGCAAAAGCCTTTGCCGGAGACTTATCTTGATCATCCCTTGCGAGGAAATTGGA
AAAGCTATCGGGATGCCCATATCGAGCCTGACTGGTTACTGATCTATCGCATCGAAGGTAATGAGTCACAACTGGCTAGA
ACCGGGACCCATGCTGATTTGTTCACTGAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9344.74 Da        Isoelectric Point: 4.8411

>AT135646 WP_147185807.1 NZ_CP042382:c3514384-3514127 [Pistricoccus aurantiacus]
MSTDTVVRARIDSETKAKATEALDAMGLSVSDAIRLLMLRIAEEKRLPFTVQVPSATTAKAMEELESGKGKRFDDAETLF
KDLNI

Download         Length: 258 bp

>AT135646 NZ_CP042382:c3514384-3514127 [Pistricoccus aurantiacus]
ATGAGTACCGATACCGTTGTCAGAGCCCGCATCGACAGTGAGACGAAAGCCAAGGCCACCGAGGCGCTTGACGCCATGGG
GCTGTCCGTCTCCGATGCCATTCGATTGTTGATGCTGAGAATCGCCGAGGAAAAACGCCTGCCTTTTACCGTGCAGGTGC
CAAGCGCCACCACGGCCAAGGCGATGGAAGAGTTGGAGAGTGGCAAGGGAAAGCGTTTCGATGATGCCGAGACCCTGTTC
AAGGATCTAAATATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References