Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3202357..3202913 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FGL86_RS15155 Protein ID WP_147185480.1
Coordinates 3202623..3202913 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FGL86_RS15150 Protein ID WP_147185478.1
Coordinates 3202357..3202635 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS15130 3197657..3199411 + 1755 WP_147185472.1 type IV-A pilus assembly ATPase PilB -
FGL86_RS15135 3199534..3200763 + 1230 WP_147185474.1 type II secretion system F family protein -
FGL86_RS15140 3200775..3201650 + 876 WP_147185476.1 A24 family peptidase -
FGL86_RS15145 3201653..3202255 + 603 WP_147186233.1 dephospho-CoA kinase -
FGL86_RS15150 3202357..3202635 + 279 WP_147185478.1 CopG family ribbon-helix-helix protein Antitoxin
FGL86_RS15155 3202623..3202913 + 291 WP_147185480.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL86_RS15160 3202999..3203238 + 240 WP_147185482.1 DNA gyrase inhibitor YacG -
FGL86_RS15165 3203250..3204134 + 885 WP_147185484.1 DNA replication terminus site-binding protein -
FGL86_RS15170 3204152..3204412 - 261 WP_147185486.1 (Na+)-NQR maturation NqrM -
FGL86_RS15175 3204541..3205773 - 1233 WP_147185488.1 NADH:ubiquinone reductase (Na(+)-transporting) subunit F -
FGL86_RS15180 3205803..3206423 - 621 WP_186764420.1 NADH:ubiquinone reductase (Na(+)-transporting) subunit E -
FGL86_RS15185 3206424..3207092 - 669 WP_147185490.1 NADH:ubiquinone reductase (Na(+)-transporting) subunit D -
FGL86_RS15190 3207095..3207877 - 783 WP_147185492.1 Na(+)-translocating NADH-quinone reductase subunit C -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11399.99 Da        Isoelectric Point: 9.4118

>T135645 WP_147185480.1 NZ_CP042382:3202623-3202913 [Pistricoccus aurantiacus]
MPHLKWSTRSLNDMQRLHRFLAYKDQDAASRAIKSIRYGVRVLAHQPQAGRPIDDMEPEYREWLIDFGNSGYIVRYRIDN
DTIILLAIRHQKEADF

Download         Length: 291 bp

>T135645 NZ_CP042382:3202623-3202913 [Pistricoccus aurantiacus]
TTGCCACACCTGAAATGGTCAACCCGCTCATTAAACGATATGCAGCGTCTTCATCGTTTCCTTGCGTACAAGGATCAGGA
TGCTGCCAGTCGCGCGATAAAATCGATCCGTTACGGAGTAAGAGTTCTAGCTCATCAGCCTCAGGCGGGGCGACCCATTG
ATGACATGGAACCAGAGTATCGAGAATGGCTAATCGACTTTGGCAATAGCGGCTATATCGTTCGATACCGTATCGACAAC
GACACCATTATATTGCTGGCTATCCGACATCAAAAAGAAGCTGATTTTTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10892.17 Da        Isoelectric Point: 5.2526

>AT135645 WP_147185478.1 NZ_CP042382:3202357-3202635 [Pistricoccus aurantiacus]
MASPTSIKLDDNLKERIQHLAEERRRSAHWVMREAISQYVEREEKREAFKRDTLKAWEEYQRTGLHLTLEEADAWLARLE
AGEDAEIPTCHT

Download         Length: 279 bp

>AT135645 NZ_CP042382:3202357-3202635 [Pistricoccus aurantiacus]
ATGGCATCGCCAACTTCCATCAAACTCGATGACAACTTGAAAGAGCGGATTCAGCATCTCGCAGAAGAACGCCGACGCTC
GGCGCACTGGGTCATGCGTGAAGCCATCAGTCAGTATGTCGAACGTGAAGAAAAACGCGAAGCGTTCAAACGAGACACGC
TTAAGGCTTGGGAAGAATACCAGCGCACCGGCCTGCATCTGACGCTGGAAGAAGCGGACGCTTGGCTTGCGAGACTTGAA
GCTGGCGAGGACGCAGAGATACCCACTTGCCACACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References