Detailed information of TA system TA135640

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1267528..1268041
• Replicon: chromosome
• Accession: NZ_CP042382
• Organism: Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FGL86_RS06110
• Protein ID: WP_147183751.1
• Coordinates: 1267528..1267794 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FGL86_RS06115
• Protein ID: WP_147183752.1
• Coordinates: 1267784..1268041 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FGL86_RS06090	1262618..1263825	+	1208	WP_147183716.1	IS3 family transposase	-
FGL86_RS06100	1264360..1266231	+	1872	WP_147183749.1	helicase/relaxase domain-containing protein	-
FGL86_RS06105	1266224..1267177	+	954	WP_147183750.1	site-specific integrase	-
FGL86_RS06110	1267528..1267794	+	267	WP_147183751.1	BrnT family toxin	Toxin
FGL86_RS06115	1267784..1268041	+	258	WP_147183752.1	CopG family transcriptional regulator	Antitoxin
FGL86_RS06120	1268319..1269134	-	816	WP_147183753.1	MBL fold metallo-hydrolase	-
FGL86_RS06125	1269322..1269639	+	318	WP_147183754.1	hypothetical protein	-
FGL86_RS06130	1269848..1272046	+	2199	WP_147183755.1	MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (33-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 9751.21 Da
• Isoelectric Point: 10.4493

>T135640 WP_147183751.1 NZ_CP042382:1267528-1267794 [Pistricoccus aurantiacus]
MRVSATVCSKGGVGKTTVTANLSGLLADAGFRVLLLEIRAKSEDEQRFLLIGQIDGKHWSAVVAYREGRTRLISARRSRK
QEVELYES

Nucleotide

• Length: 267 bp

>T135640 NZ_CP042382:1267528-1267794 [Pistricoccus aurantiacus]
ATGCGTGTTTCCGCGACGGTCTGTTCCAAGGGTGGCGTGGGCAAGACCACCGTCACCGCCAATCTGAGCGGTTTGCTGGC
TGACGCCGGCTTCCGGGTACTGCTGCTGGAAATCCGTGCAAAATCGGAAGACGAACAACGGTTCTTGCTGATCGGCCAAA
TTGATGGAAAGCACTGGTCGGCTGTCGTCGCATACAGGGAAGGCCGTACTCGTCTGATTTCAGCCAGGCGCTCTCGCAAG
CAGGAGGTTGAGCTCTATGAAAGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9556.75 Da
• Isoelectric Point: 4.6558

>AT135640 WP_147183752.1 NZ_CP042382:1267784-1268041 [Pistricoccus aurantiacus]
MKAKKFEEDQEDIVDDLDLPTARRVNQEQKRINVDFPAWVVESLDREAARIGITRQSIIKVWLVECPQAEAANKPLNGDA
ASGAH

Nucleotide

• Length: 258 bp

>AT135640 NZ_CP042382:1267784-1268041 [Pistricoccus aurantiacus]
ATGAAAGCTAAAAAATTCGAGGAGGATCAGGAAGATATTGTTGATGATCTCGACCTGCCCACAGCTCGCCGTGTTAACCA
GGAGCAAAAGCGAATCAACGTTGATTTTCCGGCTTGGGTTGTAGAGTCGTTGGATCGTGAGGCGGCACGTATTGGTATCA
CACGCCAATCAATCATCAAGGTATGGCTTGTTGAATGCCCTCAGGCAGAAGCCGCTAACAAGCCGCTCAATGGTGACGCC
GCAAGCGGCGCACATTAG