Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-StbC |
Location | 791805..792478 | Replicon | chromosome |
Accession | NZ_CP042382 | ||
Organism | Pistricoccus aurantiacus strain CBA4606 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | FGL86_RS03755 | Protein ID | WP_147183341.1 |
Coordinates | 792056..792478 (+) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | FGL86_RS03750 | Protein ID | WP_147183340.1 |
Coordinates | 791805..792059 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FGL86_RS03720 | 786880..787569 | + | 690 | WP_147186074.1 | PIG-L family deacetylase | - |
FGL86_RS03725 | 787566..788165 | + | 600 | WP_147183335.1 | class I SAM-dependent methyltransferase | - |
FGL86_RS03730 | 788211..788921 | + | 711 | WP_147183336.1 | glycosyltransferase | - |
FGL86_RS03735 | 788936..789325 | - | 390 | WP_147183337.1 | Lin0512 family protein | - |
FGL86_RS03740 | 789318..789671 | - | 354 | WP_147183338.1 | Lin0512 family protein | - |
FGL86_RS03745 | 789815..791632 | + | 1818 | WP_147183339.1 | aminopeptidase P family protein | - |
FGL86_RS03750 | 791805..792059 | + | 255 | WP_147183340.1 | plasmid stabilization protein | Antitoxin |
FGL86_RS03755 | 792056..792478 | + | 423 | WP_147183341.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
FGL86_RS03760 | 792568..793341 | - | 774 | WP_147183342.1 | glucose 1-dehydrogenase | - |
FGL86_RS03765 | 793447..793884 | - | 438 | WP_147183343.1 | BLUF domain-containing protein | - |
FGL86_RS03770 | 793899..795557 | - | 1659 | WP_186764467.1 | EAL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 15089.39 Da Isoelectric Point: 5.8431
>T135638 WP_147183341.1 NZ_CP042382:792056-792478 [Pistricoccus aurantiacus]
MIVLDTNVISEAMKPGPHPAVRAWLNAQVSGMLYLSSITLAELSFGIAALPNGKRKDTLTVALDGLMALFKDRILSFDPT
AARQYAELAVTARTAGRGFPIPDGYIAAIAVSRGFQVASRDTAPFEAANVDVINPWEWKE
MIVLDTNVISEAMKPGPHPAVRAWLNAQVSGMLYLSSITLAELSFGIAALPNGKRKDTLTVALDGLMALFKDRILSFDPT
AARQYAELAVTARTAGRGFPIPDGYIAAIAVSRGFQVASRDTAPFEAANVDVINPWEWKE
Download Length: 423 bp
>T135638 NZ_CP042382:792056-792478 [Pistricoccus aurantiacus]
ATGATCGTACTGGATACCAACGTCATTTCCGAGGCAATGAAGCCCGGCCCTCACCCGGCGGTAAGAGCATGGCTCAATGC
TCAAGTGTCCGGAATGCTGTATCTGTCCAGCATTACGTTGGCCGAGTTGTCGTTTGGCATTGCAGCCCTACCCAATGGCA
AGCGCAAGGATACGTTGACTGTTGCCCTGGACGGGCTCATGGCACTTTTCAAGGATCGCATTCTGTCCTTTGATCCAACC
GCCGCACGCCAGTACGCCGAGCTGGCTGTTACGGCCAGAACTGCCGGGCGCGGCTTTCCGATACCGGATGGCTATATTGC
GGCTATTGCCGTATCACGAGGCTTTCAGGTTGCGTCTCGTGATACGGCTCCCTTTGAAGCGGCCAACGTCGATGTAATCA
ATCCGTGGGAATGGAAAGAATAG
ATGATCGTACTGGATACCAACGTCATTTCCGAGGCAATGAAGCCCGGCCCTCACCCGGCGGTAAGAGCATGGCTCAATGC
TCAAGTGTCCGGAATGCTGTATCTGTCCAGCATTACGTTGGCCGAGTTGTCGTTTGGCATTGCAGCCCTACCCAATGGCA
AGCGCAAGGATACGTTGACTGTTGCCCTGGACGGGCTCATGGCACTTTTCAAGGATCGCATTCTGTCCTTTGATCCAACC
GCCGCACGCCAGTACGCCGAGCTGGCTGTTACGGCCAGAACTGCCGGGCGCGGCTTTCCGATACCGGATGGCTATATTGC
GGCTATTGCCGTATCACGAGGCTTTCAGGTTGCGTCTCGTGATACGGCTCCCTTTGAAGCGGCCAACGTCGATGTAATCA
ATCCGTGGGAATGGAAAGAATAG
Antitoxin
Download Length: 85 a.a. Molecular weight: 9309.47 Da Isoelectric Point: 4.8550
>AT135638 WP_147183340.1 NZ_CP042382:791805-792059 [Pistricoccus aurantiacus]
MGMMTVRNIPDDVHSAIKARARRHNRSAEAEVRAILEEATQSERSIPMGDALAELGRKVGLTNEDFAVLEQMRDNTAAEP
VSFE
MGMMTVRNIPDDVHSAIKARARRHNRSAEAEVRAILEEATQSERSIPMGDALAELGRKVGLTNEDFAVLEQMRDNTAAEP
VSFE
Download Length: 255 bp
>AT135638 NZ_CP042382:791805-792059 [Pistricoccus aurantiacus]
ATGGGCATGATGACAGTCAGGAACATCCCTGATGACGTACACAGCGCTATAAAAGCGAGGGCCAGGCGGCACAACCGCAG
CGCGGAAGCTGAGGTCCGTGCCATTCTGGAAGAAGCTACGCAGTCGGAAAGAAGCATTCCCATGGGGGATGCCTTGGCGG
AACTGGGGCGCAAGGTCGGGCTGACCAACGAGGATTTCGCTGTTCTTGAGCAGATGCGCGATAACACAGCGGCAGAGCCA
GTGAGTTTCGAATGA
ATGGGCATGATGACAGTCAGGAACATCCCTGATGACGTACACAGCGCTATAAAAGCGAGGGCCAGGCGGCACAACCGCAG
CGCGGAAGCTGAGGTCCGTGCCATTCTGGAAGAAGCTACGCAGTCGGAAAGAAGCATTCCCATGGGGGATGCCTTGGCGG
AACTGGGGCGCAAGGTCGGGCTGACCAACGAGGATTTCGCTGTTCTTGAGCAGATGCGCGATAACACAGCGGCAGAGCCA
GTGAGTTTCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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