Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 791805..792478 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGL86_RS03755 Protein ID WP_147183341.1
Coordinates 792056..792478 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FGL86_RS03750 Protein ID WP_147183340.1
Coordinates 791805..792059 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS03720 786880..787569 + 690 WP_147186074.1 PIG-L family deacetylase -
FGL86_RS03725 787566..788165 + 600 WP_147183335.1 class I SAM-dependent methyltransferase -
FGL86_RS03730 788211..788921 + 711 WP_147183336.1 glycosyltransferase -
FGL86_RS03735 788936..789325 - 390 WP_147183337.1 Lin0512 family protein -
FGL86_RS03740 789318..789671 - 354 WP_147183338.1 Lin0512 family protein -
FGL86_RS03745 789815..791632 + 1818 WP_147183339.1 aminopeptidase P family protein -
FGL86_RS03750 791805..792059 + 255 WP_147183340.1 plasmid stabilization protein Antitoxin
FGL86_RS03755 792056..792478 + 423 WP_147183341.1 type II toxin-antitoxin system VapC family toxin Toxin
FGL86_RS03760 792568..793341 - 774 WP_147183342.1 glucose 1-dehydrogenase -
FGL86_RS03765 793447..793884 - 438 WP_147183343.1 BLUF domain-containing protein -
FGL86_RS03770 793899..795557 - 1659 WP_186764467.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15089.39 Da        Isoelectric Point: 5.8431

>T135638 WP_147183341.1 NZ_CP042382:792056-792478 [Pistricoccus aurantiacus]
MIVLDTNVISEAMKPGPHPAVRAWLNAQVSGMLYLSSITLAELSFGIAALPNGKRKDTLTVALDGLMALFKDRILSFDPT
AARQYAELAVTARTAGRGFPIPDGYIAAIAVSRGFQVASRDTAPFEAANVDVINPWEWKE

Download         Length: 423 bp

>T135638 NZ_CP042382:792056-792478 [Pistricoccus aurantiacus]
ATGATCGTACTGGATACCAACGTCATTTCCGAGGCAATGAAGCCCGGCCCTCACCCGGCGGTAAGAGCATGGCTCAATGC
TCAAGTGTCCGGAATGCTGTATCTGTCCAGCATTACGTTGGCCGAGTTGTCGTTTGGCATTGCAGCCCTACCCAATGGCA
AGCGCAAGGATACGTTGACTGTTGCCCTGGACGGGCTCATGGCACTTTTCAAGGATCGCATTCTGTCCTTTGATCCAACC
GCCGCACGCCAGTACGCCGAGCTGGCTGTTACGGCCAGAACTGCCGGGCGCGGCTTTCCGATACCGGATGGCTATATTGC
GGCTATTGCCGTATCACGAGGCTTTCAGGTTGCGTCTCGTGATACGGCTCCCTTTGAAGCGGCCAACGTCGATGTAATCA
ATCCGTGGGAATGGAAAGAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9309.47 Da        Isoelectric Point: 4.8550

>AT135638 WP_147183340.1 NZ_CP042382:791805-792059 [Pistricoccus aurantiacus]
MGMMTVRNIPDDVHSAIKARARRHNRSAEAEVRAILEEATQSERSIPMGDALAELGRKVGLTNEDFAVLEQMRDNTAAEP
VSFE

Download         Length: 255 bp

>AT135638 NZ_CP042382:791805-792059 [Pistricoccus aurantiacus]
ATGGGCATGATGACAGTCAGGAACATCCCTGATGACGTACACAGCGCTATAAAAGCGAGGGCCAGGCGGCACAACCGCAG
CGCGGAAGCTGAGGTCCGTGCCATTCTGGAAGAAGCTACGCAGTCGGAAAGAAGCATTCCCATGGGGGATGCCTTGGCGG
AACTGGGGCGCAAGGTCGGGCTGACCAACGAGGATTTCGCTGTTCTTGAGCAGATGCGCGATAACACAGCGGCAGAGCCA
GTGAGTTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References