135637

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 778633..779107 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag FGL86_RS03680 Protein ID WP_147183329.1
Coordinates 778841..779107 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag FGL86_RS03675 Protein ID WP_147183328.1
Coordinates 778633..778857 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS03640 773764..774795 + 1032 WP_147183322.1 sodium:calcium antiporter -
FGL86_RS03645 774996..776096 + 1101 WP_147183323.1 aldo/keto reductase -
FGL86_RS03650 776236..776460 + 225 WP_147183324.1 amphi-Trp domain-containing protein -
FGL86_RS03655 776494..777519 - 1026 WP_147183325.1 DUF21 domain-containing protein -
FGL86_RS03660 777737..777988 + 252 WP_147183326.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
FGL86_RS03665 777988..778413 + 426 WP_147183327.1 type II toxin-antitoxin system VapC family toxin -
FGL86_RS03675 778633..778857 + 225 WP_147183328.1 ribbon-helix-helix protein, CopG family Antitoxin
FGL86_RS03680 778841..779107 + 267 WP_147183329.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL86_RS03685 779193..779930 + 738 WP_186764465.1 M15 family metallopeptidase -
FGL86_RS03690 780007..781923 + 1917 WP_147183330.1 protein-disulfide reductase DsbD -
FGL86_RS03695 781926..782741 + 816 WP_147186073.1 TlpA family protein disulfide reductase -
FGL86_RS03700 782813..783604 + 792 WP_147183331.1 thiol:disulfide interchange protein DsbG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(3-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10502.24 Da        Isoelectric Point: 10.8736

>T135637 WP_147183329.1 NZ_CP042382:778841-779107 [Pistricoccus aurantiacus]
MAWRIELTDDAAKQLKKIGHSDAKRIRDYLRSRIEPLENPRQLGKPLTGKLGELWRYRVGHYRIIADIDDQAIRILVIRI
GHRREIYR

Download         Length: 267 bp

>T135637 NZ_CP042382:778841-779107 [Pistricoccus aurantiacus]
TTGGCCTGGCGGATTGAACTCACCGACGACGCCGCCAAGCAACTCAAGAAGATCGGTCACAGTGACGCCAAGCGTATTCG
CGATTATCTGCGCTCACGGATCGAGCCGCTGGAAAACCCTCGGCAGCTGGGCAAACCGCTGACAGGAAAACTGGGTGAAC
TATGGCGCTATCGGGTAGGGCACTACCGCATCATTGCCGATATTGATGATCAAGCAATACGAATACTCGTCATTCGTATC
GGCCATCGCCGCGAGATTTACCGATGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8664.79 Da        Isoelectric Point: 4.4558

>AT135637 WP_147183328.1 NZ_CP042382:778633-778857 [Pistricoccus aurantiacus]
MLAIRLPVEIEERLDKLAKATGRTKTYYAREAILEYLDDLEDIYLAEQTLERVRRGETRTHTLDEVERDLGLAD

Download         Length: 225 bp

>AT135637 NZ_CP055092:862944-863210 [Shigella flexneri]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References