Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 777737..778413 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FGL86_RS03665 Protein ID WP_147183327.1
Coordinates 777988..778413 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FGL86_RS03660 Protein ID WP_147183326.1
Coordinates 777737..777988 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS03635 773028..773621 - 594 WP_147183321.1 LemA family protein -
FGL86_RS03640 773764..774795 + 1032 WP_147183322.1 sodium:calcium antiporter -
FGL86_RS03645 774996..776096 + 1101 WP_147183323.1 aldo/keto reductase -
FGL86_RS03650 776236..776460 + 225 WP_147183324.1 amphi-Trp domain-containing protein -
FGL86_RS03655 776494..777519 - 1026 WP_147183325.1 DUF21 domain-containing protein -
FGL86_RS03660 777737..777988 + 252 WP_147183326.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FGL86_RS03665 777988..778413 + 426 WP_147183327.1 type II toxin-antitoxin system VapC family toxin Toxin
FGL86_RS03675 778633..778857 + 225 WP_147183328.1 ribbon-helix-helix protein, CopG family -
FGL86_RS03680 778841..779107 + 267 WP_147183329.1 type II toxin-antitoxin system RelE/ParE family toxin -
FGL86_RS03685 779193..779930 + 738 WP_186764465.1 M15 family metallopeptidase -
FGL86_RS03690 780007..781923 + 1917 WP_147183330.1 protein-disulfide reductase DsbD -
FGL86_RS03695 781926..782741 + 816 WP_147186073.1 TlpA family protein disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-56)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16196.77 Da        Isoelectric Point: 8.0480

>T135636 WP_147183327.1 NZ_CP042382:777988-778413 [Pistricoccus aurantiacus]
MHYLVDTCVISEIVKPSPAPQVVEWLVNVEEDRLFLSVLTIGELQKGISALAAGRKRQRLQTWLDQELTRRFERRLLPID
QETAQEWGVISAQARLKGLAAPVIDTLLAATARRHNLVLITRNLRDFTPFDVRLFNPWQLD

Download         Length: 426 bp

>T135636 NZ_CP042382:777988-778413 [Pistricoccus aurantiacus]
ATGCACTATCTCGTCGATACCTGTGTGATTTCCGAGATAGTCAAGCCTTCCCCCGCACCGCAGGTCGTCGAATGGCTGGT
AAATGTGGAAGAAGATCGTTTGTTTTTAAGCGTACTGACGATAGGTGAATTACAAAAAGGAATTTCGGCACTTGCTGCCG
GTAGAAAACGCCAGCGGCTTCAAACATGGCTAGATCAAGAGCTTACCCGGCGTTTTGAAAGACGCTTATTGCCGATCGAT
CAGGAAACGGCGCAAGAGTGGGGCGTTATCAGCGCCCAGGCACGCCTCAAAGGATTGGCTGCTCCGGTAATCGATACCCT
GCTGGCCGCTACGGCACGCCGACATAATCTAGTATTGATCACACGAAACCTTCGCGACTTTACTCCCTTCGATGTCCGAT
TATTTAATCCTTGGCAACTCGACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9349.59 Da        Isoelectric Point: 4.6775

>AT135636 WP_147183326.1 NZ_CP042382:777737-777988 [Pistricoccus aurantiacus]
VEWQLQLAKSKLSELVETTSREGPQVITVRGKRKVVMISAEEYDALVQRNSQGSLVEFLRASPLAEVELDLERSHDEGRE
VAL

Download         Length: 252 bp

>AT135636 NZ_CP042382:777737-777988 [Pistricoccus aurantiacus]
GTGGAATGGCAGCTGCAATTGGCTAAAAGCAAGCTTAGCGAACTGGTCGAAACGACAAGCCGTGAGGGACCCCAAGTCAT
CACCGTTCGCGGTAAGCGCAAAGTAGTGATGATTTCCGCGGAAGAGTACGACGCCCTAGTACAACGGAATTCGCAAGGCT
CGCTAGTCGAGTTTCTGCGCGCCTCACCCTTGGCAGAGGTTGAGCTTGATCTTGAGCGGTCACATGATGAAGGACGCGAG
GTAGCACTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References