Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-Phd |
Location | 777737..778413 | Replicon | chromosome |
Accession | NZ_CP042382 | ||
Organism | Pistricoccus aurantiacus strain CBA4606 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | FGL86_RS03665 | Protein ID | WP_147183327.1 |
Coordinates | 777988..778413 (+) | Length | 142 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | FGL86_RS03660 | Protein ID | WP_147183326.1 |
Coordinates | 777737..777988 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FGL86_RS03635 | 773028..773621 | - | 594 | WP_147183321.1 | LemA family protein | - |
FGL86_RS03640 | 773764..774795 | + | 1032 | WP_147183322.1 | sodium:calcium antiporter | - |
FGL86_RS03645 | 774996..776096 | + | 1101 | WP_147183323.1 | aldo/keto reductase | - |
FGL86_RS03650 | 776236..776460 | + | 225 | WP_147183324.1 | amphi-Trp domain-containing protein | - |
FGL86_RS03655 | 776494..777519 | - | 1026 | WP_147183325.1 | DUF21 domain-containing protein | - |
FGL86_RS03660 | 777737..777988 | + | 252 | WP_147183326.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
FGL86_RS03665 | 777988..778413 | + | 426 | WP_147183327.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
FGL86_RS03675 | 778633..778857 | + | 225 | WP_147183328.1 | ribbon-helix-helix protein, CopG family | - |
FGL86_RS03680 | 778841..779107 | + | 267 | WP_147183329.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
FGL86_RS03685 | 779193..779930 | + | 738 | WP_186764465.1 | M15 family metallopeptidase | - |
FGL86_RS03690 | 780007..781923 | + | 1917 | WP_147183330.1 | protein-disulfide reductase DsbD | - |
FGL86_RS03695 | 781926..782741 | + | 816 | WP_147186073.1 | TlpA family protein disulfide reductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 16196.77 Da Isoelectric Point: 8.0480
>T135636 WP_147183327.1 NZ_CP042382:777988-778413 [Pistricoccus aurantiacus]
MHYLVDTCVISEIVKPSPAPQVVEWLVNVEEDRLFLSVLTIGELQKGISALAAGRKRQRLQTWLDQELTRRFERRLLPID
QETAQEWGVISAQARLKGLAAPVIDTLLAATARRHNLVLITRNLRDFTPFDVRLFNPWQLD
MHYLVDTCVISEIVKPSPAPQVVEWLVNVEEDRLFLSVLTIGELQKGISALAAGRKRQRLQTWLDQELTRRFERRLLPID
QETAQEWGVISAQARLKGLAAPVIDTLLAATARRHNLVLITRNLRDFTPFDVRLFNPWQLD
Download Length: 426 bp
>T135636 NZ_CP042382:777988-778413 [Pistricoccus aurantiacus]
ATGCACTATCTCGTCGATACCTGTGTGATTTCCGAGATAGTCAAGCCTTCCCCCGCACCGCAGGTCGTCGAATGGCTGGT
AAATGTGGAAGAAGATCGTTTGTTTTTAAGCGTACTGACGATAGGTGAATTACAAAAAGGAATTTCGGCACTTGCTGCCG
GTAGAAAACGCCAGCGGCTTCAAACATGGCTAGATCAAGAGCTTACCCGGCGTTTTGAAAGACGCTTATTGCCGATCGAT
CAGGAAACGGCGCAAGAGTGGGGCGTTATCAGCGCCCAGGCACGCCTCAAAGGATTGGCTGCTCCGGTAATCGATACCCT
GCTGGCCGCTACGGCACGCCGACATAATCTAGTATTGATCACACGAAACCTTCGCGACTTTACTCCCTTCGATGTCCGAT
TATTTAATCCTTGGCAACTCGACTGA
ATGCACTATCTCGTCGATACCTGTGTGATTTCCGAGATAGTCAAGCCTTCCCCCGCACCGCAGGTCGTCGAATGGCTGGT
AAATGTGGAAGAAGATCGTTTGTTTTTAAGCGTACTGACGATAGGTGAATTACAAAAAGGAATTTCGGCACTTGCTGCCG
GTAGAAAACGCCAGCGGCTTCAAACATGGCTAGATCAAGAGCTTACCCGGCGTTTTGAAAGACGCTTATTGCCGATCGAT
CAGGAAACGGCGCAAGAGTGGGGCGTTATCAGCGCCCAGGCACGCCTCAAAGGATTGGCTGCTCCGGTAATCGATACCCT
GCTGGCCGCTACGGCACGCCGACATAATCTAGTATTGATCACACGAAACCTTCGCGACTTTACTCCCTTCGATGTCCGAT
TATTTAATCCTTGGCAACTCGACTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9349.59 Da Isoelectric Point: 4.6775
>AT135636 WP_147183326.1 NZ_CP042382:777737-777988 [Pistricoccus aurantiacus]
VEWQLQLAKSKLSELVETTSREGPQVITVRGKRKVVMISAEEYDALVQRNSQGSLVEFLRASPLAEVELDLERSHDEGRE
VAL
VEWQLQLAKSKLSELVETTSREGPQVITVRGKRKVVMISAEEYDALVQRNSQGSLVEFLRASPLAEVELDLERSHDEGRE
VAL
Download Length: 252 bp
>AT135636 NZ_CP042382:777737-777988 [Pistricoccus aurantiacus]
GTGGAATGGCAGCTGCAATTGGCTAAAAGCAAGCTTAGCGAACTGGTCGAAACGACAAGCCGTGAGGGACCCCAAGTCAT
CACCGTTCGCGGTAAGCGCAAAGTAGTGATGATTTCCGCGGAAGAGTACGACGCCCTAGTACAACGGAATTCGCAAGGCT
CGCTAGTCGAGTTTCTGCGCGCCTCACCCTTGGCAGAGGTTGAGCTTGATCTTGAGCGGTCACATGATGAAGGACGCGAG
GTAGCACTATAA
GTGGAATGGCAGCTGCAATTGGCTAAAAGCAAGCTTAGCGAACTGGTCGAAACGACAAGCCGTGAGGGACCCCAAGTCAT
CACCGTTCGCGGTAAGCGCAAAGTAGTGATGATTTCCGCGGAAGAGTACGACGCCCTAGTACAACGGAATTCGCAAGGCT
CGCTAGTCGAGTTTCTGCGCGCCTCACCCTTGGCAGAGGTTGAGCTTGATCTTGAGCGGTCACATGATGAAGGACGCGAG
GTAGCACTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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