Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3801941..3802558 Replicon chromosome
Accession NZ_CP042357
Organism Rahnella aquatilis strain H145

Toxin (Protein)


Gene name Hha Uniprot ID H8NYI7
Locus tag FS594_RS17930 Protein ID WP_013576617.1
Coordinates 3802355..3802558 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag FS594_RS17925 Protein ID WP_129952820.1
Coordinates 3801941..3802309 (+) Length 123 a.a.

Genomic Context

FS594_RS17895FS594_RS17900FS594_RS17920FS594_RS17925FS594_RS17930FS594_RS17940FS594_RS17945FS594_RS17905FS594_RS17910FS594_RS17915FS594_RS17935
Location: 3797947..3798201 (255 bp)
Type: Others
Protein ID: WP_120506405.1
Location: 3798223..3798363 (141 bp)
Type: Others
Protein ID: WP_013576611.1
Location: 3801356..3801709 (354 bp)
Type: Others
Protein ID: WP_129992079.1
Location: 3801941..3802309 (369 bp)
Type: Antitoxin
Protein ID: WP_129952820.1
Location: 3802355..3802558 (204 bp)
Type: Toxin
Protein ID: WP_013576617.1
Location: 3803730..3805517 (1788 bp)
Type: Others
Protein ID: WP_235173218.1
Location: 3805592..3806941 (1350 bp)
Type: Others
Protein ID: WP_235173219.1
Location: 3798486..3799364 (879 bp)
Type: Others
Protein ID: WP_129992124.1
Location: 3799393..3800250 (858 bp)
Type: Others
Protein ID: WP_217139370.1
Location: 3800247..3800975 (729 bp)
Type: Others
Protein ID: WP_205951586.1
Location: 3802634..3803590 (957 bp)
Type: Others
Protein ID: WP_235173217.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FS594_RS17895 (FS594_17960)3797947..3798201+255WP_120506405.1type B 50S ribosomal protein L31-
FS594_RS17900 (FS594_17965)3798223..3798363+141WP_013576611.1type B 50S ribosomal protein L36-
FS594_RS17905 (FS594_17970)3798486..3799364-879WP_129992124.1metal ABC transporter substrate-binding protein-
FS594_RS17910 (FS594_17975)3799393..3800250-858WP_217139370.1metal ABC transporter permease-
FS594_RS17915 (FS594_17980)3800247..3800975-729WP_205951586.1ABC transporter ATP-binding protein-
FS594_RS17920 (FS594_17985)3801356..3801709+354WP_129992079.1hypothetical protein-
FS594_RS17925 (FS594_17990)3801941..3802309+369WP_129952820.1Hha toxicity modulator TomBAntitoxin
FS594_RS17930 (FS594_17995)3802355..3802558+204WP_013576617.1HHA domain-containing proteinToxin
FS594_RS17935 (FS594_18000)3802634..3803590-957WP_235173217.1LysR family transcriptional regulator-
FS594_RS17940 (FS594_18005)3803730..3805517+1788WP_235173218.1adenine deaminase C-terminal domain-containing protein-
FS594_RS17945 (FS594_18010)3805592..3806941+1350WP_235173219.1NCS2 family permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8114.45 Da        Isoelectric Point: 6.9764

>T135582 WP_013576617.1 NZ_CP042357:3802355-3802558 [Rahnella aquatilis]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVSVWKFVR

Download         Length: 204 bp

>T135582 NZ_CP042357:3802355-3802558 [Rahnella aquatilis]
ATGAACAAAATCGACTATTTGATGCGTTTAAGAAAATGCACCACAATCGATACACTCGAACGTGTTATTGAGAAAAATAA
GTATGAACTTTCCGACGACGAACTGGAATTGTTTTACTCGGCAGCTGACCATCGTTTAGCGGAGCTAACGATGAACAAAC
TGTACGATAAAATTCCGGTATCAGTCTGGAAATTTGTACGCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14347.14 Da        Isoelectric Point: 4.8936

>AT135582 WP_129952820.1 NZ_CP042357:3801941-3802309 [Rahnella aquatilis]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKYPADNHLSDLVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp

>AT135582 NZ_CP042357:3801941-3802309 [Rahnella aquatilis]
ATGGATGAGTACTCGCCTAAGCGGCACGATATCGCTCAGTTACGCTACCTGAATGAAATGCTGTACGATGAAGGGATTGC
AACACTGGGTGACAGCCATCATGGCTGGGTTAATGATCCGACTTCGGCCGTTAACCTACAGCTCAATGAACTGATTGAGC
ACATTGCATCCTTTGTGATGAGTTTTAAAATTAAGTATCCGGCTGATAACCATTTAAGTGATCTGGTTGAAGAGTATCTG
GATGATACCTACACCCTGTTCAGCAATTATGGAATTAACGATTCTGATTTGCGTCAATGGCAAAAGACCAAGAAGCGCTT
ATTCAGAATGTTCTCAGGGGACTACATCTGTACCCTAATGAAGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH8NYI7

Antitoxin

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Source
ID
Structure
No matching records found

References