Detailed information of TA system TA135572

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1514992..1515908
• Replicon: chromosome
• Accession: NZ_CP042357
• Organism: Rahnella aquatilis strain H145

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FS594_RS07125
• Protein ID: WP_129952431.1
• Coordinates: 1514992..1515450 (-)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FS594_RS07130
• Protein ID: WP_129952432.1
• Coordinates: 1515447..1515908 (-)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FS594_RS07100 (FS594_07120)	1510163..1511848	+	1686	WP_235173859.1	choline dehydrogenase	-
FS594_RS07105 (FS594_07125)	1511939..1512397	+	459	WP_129952428.1	GNAT family N-acetyltransferase	-
FS594_RS07110 (FS594_07130)	1513043..1513972	-	930	WP_129991275.1	LysR family transcriptional regulator	-
FS594_RS07115 (FS594_07135)	1514074..1514508	+	435	WP_217139064.1	DMT family transporter	-
FS594_RS07120 (FS594_07140)	1514512..1514964	+	453	WP_129952430.1	DMT family transporter	-
FS594_RS07125 (FS594_07145)	1514992..1515450	-	459	WP_129952431.1	RES family NAD+ phosphorylase	Toxin
FS594_RS07130 (FS594_07150)	1515447..1515908	-	462	WP_129952432.1	DUF2384 domain-containing protein	Antitoxin
FS594_RS07135 (FS594_07155)	1516259..1517146	+	888	WP_129952433.1	nucleoside-specific channel-forming protein Tsx	-
FS594_RS07140 (FS594_07160)	1517332..1518927	+	1596	WP_129952434.1	ABC-F family ATPase	-
FS594_RS07145 (FS594_07165)	1519197..1519958	-	762	WP_217139067.1	molybdopterin-synthase adenylyltransferase MoeB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (2-135)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (34-95)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17105.55 Da
• Isoelectric Point: 4.4886

>T135572 WP_129952431.1 NZ_CP042357:c1515450-1514992 [Rahnella aquatilis]
MKLFRIVQTRHLATAWSGAGAQLYGGRWNPPGRPVVYVTTSISLAILEILVHVQNSMLMRAYTLLSIEVPEEWLDTLEVS
ELPADWRSASAPDSTQRQGDDWLEEGEYVGLKVPSVIVPSEYNVLLNPLHPTFGDLLSSVEREPMMFDPRLQ

Nucleotide

• Length: 459 bp

>T135572 NZ_CP042357:c1515450-1514992 [Rahnella aquatilis]
TTGAAGCTGTTTCGTATCGTGCAGACCCGCCATCTGGCCACAGCCTGGTCGGGAGCCGGTGCGCAACTTTATGGCGGCCG
CTGGAATCCGCCGGGCAGACCGGTAGTCTATGTCACCACCAGCATCTCGCTGGCGATTCTGGAAATTCTGGTGCATGTGC
AAAACAGTATGCTGATGCGCGCCTATACTTTACTGAGTATTGAAGTACCGGAGGAATGGCTTGATACGCTTGAAGTTTCA
GAGCTGCCCGCCGACTGGCGCAGTGCATCAGCACCTGACAGCACACAACGTCAGGGTGATGACTGGCTGGAGGAAGGTGA
GTATGTCGGGCTGAAAGTGCCGTCAGTGATTGTGCCGTCAGAATACAACGTATTACTTAATCCGCTGCACCCGACGTTTG
GGGATTTGCTGAGTTCTGTCGAACGCGAACCGATGATGTTTGACCCGCGCCTTCAGTAA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 16475.77 Da
• Isoelectric Point: 7.0196

>AT135572 WP_129952432.1 NZ_CP042357:c1515908-1515447 [Rahnella aquatilis]
MNSKITGLSSGSVQDSATPLWQSAGLPASSGISLINAIQKGFPVDSISRLNTELGWPKMVLLEIMGINERNYARRKAGNG
LLKSEESERVARLVRIVDAATDLFEGDRVSALEWFTRPAPALDGSRPLELLSSEAGAVEVSRLIGRLQHGVFS

Nucleotide

• Length: 462 bp

>AT135572 NZ_CP042357:c1515908-1515447 [Rahnella aquatilis]
ATGAATTCAAAAATTACCGGGCTGTCTTCCGGCTCTGTGCAAGATTCTGCAACGCCGCTTTGGCAATCTGCGGGCCTGCC
CGCAAGCAGCGGAATCAGTTTGATAAATGCCATACAAAAAGGGTTTCCGGTTGATAGTATCAGCCGTCTTAATACTGAGC
TGGGATGGCCAAAAATGGTGTTACTGGAAATCATGGGCATTAATGAACGCAACTATGCGCGGCGTAAAGCCGGGAACGGC
TTGCTGAAAAGTGAAGAGAGTGAACGGGTGGCACGGCTGGTTCGCATCGTGGATGCCGCCACTGATTTGTTCGAAGGTGA
TCGTGTATCGGCGCTCGAATGGTTCACCCGCCCTGCTCCGGCACTCGATGGTTCACGTCCGCTGGAACTGCTGTCTTCTG
AAGCTGGCGCGGTAGAAGTCAGCCGTCTGATTGGTCGTCTCCAGCACGGTGTTTTCAGTTGA