Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 846841..847540 Replicon chromosome
Accession NZ_CP042357
Organism Rahnella aquatilis strain H145

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag FS594_RS04045 Protein ID WP_129954896.1
Coordinates 847088..847540 (+) Length 151 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag FS594_RS04040 Protein ID WP_129955005.1
Coordinates 846841..847107 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FS594_RS04010 (FS594_04045) 842024..842329 - 306 WP_129954891.1 DUF883 family protein -
FS594_RS04015 (FS594_04050) 842604..843797 + 1194 WP_129954892.1 MFS transporter -
FS594_RS04020 (FS594_04055) 843927..844262 + 336 WP_013574102.1 DUF2002 family protein -
FS594_RS04025 (FS594_04060) 844322..844762 - 441 WP_129954893.1 DUF1198 domain-containing protein -
FS594_RS04030 (FS594_04065) 844976..845506 + 531 WP_129992023.1 class IV adenylate cyclase -
FS594_RS04035 (FS594_04070) 845570..846562 - 993 WP_217157877.1 tRNA-modifying protein YgfZ -
FS594_RS04040 (FS594_04075) 846841..847107 + 267 WP_129955005.1 FAD assembly factor SdhE Antitoxin
FS594_RS04045 (FS594_04080) 847088..847540 + 453 WP_129954896.1 protein YgfX Toxin
FS594_RS04050 (FS594_04085) 847586..848104 - 519 WP_013574110.1 flavodoxin FldB -
FS594_RS04055 (FS594_04090) 848252..849163 + 912 WP_217137562.1 site-specific tyrosine recombinase XerD -
FS594_RS04060 (FS594_04095) 849189..849908 + 720 WP_129954897.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
FS594_RS04065 (FS594_04100) 849915..851648 + 1734 WP_235173721.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-140)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 151 a.a.        Molecular weight: 17501.82 Da        Isoelectric Point: 11.8346

>T135571 WP_129954896.1 NZ_CP042357:847088-847540 [Rahnella aquatilis]
VALWRCDLRVSWRSQLISLGCYGGVMLLILLAPWPAGYWPVWMTLLLLVLFECIRSQRRITARTGEMILLEDNRLLWRGH
EWQIKQPVWMISHGVLLSLRREKRKGGLAQAMRSSRQRLWLASDSMSLEEWRRLRQILLSGAPRSPAKPG

Download         Length: 453 bp

>T135571 NZ_CP042357:847088-847540 [Rahnella aquatilis]
GTGGCCCTGTGGCGATGTGATCTCCGGGTGTCCTGGCGCAGTCAGCTCATTTCACTGGGATGTTACGGTGGCGTGATGCT
GCTTATTTTGCTGGCACCCTGGCCTGCAGGTTACTGGCCGGTATGGATGACGTTGCTTTTGCTGGTGTTGTTTGAATGCA
TCCGTAGCCAGCGGCGCATTACAGCACGCACGGGCGAAATGATCCTGCTTGAAGATAATCGTCTTTTGTGGCGCGGCCAT
GAATGGCAGATTAAACAGCCGGTATGGATGATAAGCCATGGTGTGCTGCTCTCGTTGCGTCGCGAAAAGCGTAAAGGCGG
GCTGGCACAGGCGATGCGCAGTTCAAGGCAGCGGTTATGGCTGGCATCGGACAGCATGAGTCTGGAAGAATGGCGGCGGT
TGCGACAGATATTGCTCAGCGGTGCACCGCGCAGCCCGGCAAAACCGGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10450.94 Da        Isoelectric Point: 5.1114

>AT135571 WP_129955005.1 NZ_CP042357:846841-847107 [Rahnella aquatilis]
MDINNRSRVHWACRRGMRELDISIMPFFEYEYDSLSDTDKEVFVRLLTCDDPDLFNWLMNHGEPKDTELQRMVALIQTRN
KARGPVAM

Download         Length: 267 bp

>AT135571 NZ_CP042357:846841-847107 [Rahnella aquatilis]
CTGGATATTAATAATCGTTCCCGCGTTCACTGGGCTTGCCGCCGCGGTATGCGCGAGCTGGATATCTCCATCATGCCGTT
CTTCGAGTATGAATATGATTCGCTGAGCGATACTGATAAAGAAGTGTTTGTCCGCCTGCTGACCTGTGACGACCCGGATT
TGTTCAACTGGCTGATGAATCACGGTGAACCGAAAGACACCGAATTACAGCGTATGGTTGCCCTTATTCAGACTCGAAAC
AAAGCCCGTGGCCCTGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References