Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 26363..26885 Replicon chromosome
Accession NZ_CP042357
Organism Rahnella aquatilis strain H145

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FS594_RS00120 Protein ID WP_129954049.1
Coordinates 26601..26885 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H8NLY8
Locus tag FS594_RS00115 Protein ID WP_013573376.1
Coordinates 26363..26611 (+) Length 83 a.a.

Genomic Context

FS594_RS00110FS594_RS00115FS594_RS00120FS594_RS00125FS594_RS00130FS594_RS00095FS594_RS00100FS594_RS00105FS594_RS00135
Location: 24281..26287 (2007 bp)
Type: Others
Protein ID: WP_235173492.1
Location: 26363..26611 (249 bp)
Type: Antitoxin
Protein ID: WP_013573376.1
Location: 26601..26885 (285 bp)
Type: Toxin
Protein ID: WP_129954049.1
Location: 27131..28045 (915 bp)
Type: Others
Protein ID: WP_014333298.1
Location: 28055..30124 (2070 bp)
Type: Others
Protein ID: WP_235173493.1
Location: 22193..22855 (663 bp)
Type: Others
Protein ID: WP_129991541.1
Location: 23077..23520 (444 bp)
Type: Others
Protein ID: WP_129954054.1
Location: 23517..24089 (573 bp)
Type: Others
Protein ID: WP_217158905.1
Location: 30190..31479 (1290 bp)
Type: Others
Protein ID: WP_235173494.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FS594_RS00095 (FS594_00095)22193..22855-663WP_129991541.1OmpA family lipoprotein-
FS594_RS00100 (FS594_00100)23077..23520-444WP_129954054.1N-acetyltransferase-
FS594_RS00105 (FS594_00105)23517..24089-573WP_217158905.1DNA-3-methyladenine glycosylase I-
FS594_RS00110 (FS594_00110)24281..26287+2007WP_235173492.1autotransporter domain-containing protein-
FS594_RS00115 (FS594_00115)26363..26611+249WP_013573376.1plasmid stabilization proteinAntitoxin
FS594_RS00120 (FS594_00120)26601..26885+285WP_129954049.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FS594_RS00125 (FS594_00125)27131..28045+915WP_014333298.1glycine--tRNA ligase subunit alpha-
FS594_RS00130 (FS594_00130)28055..30124+2070WP_235173493.1glycine--tRNA ligase subunit beta-
FS594_RS00135 (FS594_00135)30190..31479-1290WP_235173494.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10926.86 Da        Isoelectric Point: 10.5358

>T135570 WP_129954049.1 NZ_CP042357:26601-26885 [Rahnella aquatilis]
MTYKLNFFKSALKEWKALAPTIKEQFKKKLAERLENPHVASARLCGPKNNRYKIKLKSLGYRLVYQVEEQEIVVTVVAVG
KREGNEAYKLAEKR

Download         Length: 285 bp

>T135570 NZ_CP042357:26601-26885 [Rahnella aquatilis]
ATGACCTATAAACTCAACTTTTTCAAATCAGCTTTAAAAGAATGGAAAGCACTTGCCCCAACGATCAAGGAACAATTTAA
AAAGAAACTGGCTGAGCGGCTGGAGAATCCCCACGTGGCTTCTGCCCGCTTATGCGGCCCTAAAAACAACCGCTATAAAA
TCAAATTAAAGAGTCTTGGTTACCGGCTGGTTTATCAGGTAGAGGAGCAGGAAATCGTGGTGACCGTTGTCGCCGTGGGT
AAACGCGAAGGCAACGAAGCGTACAAACTGGCTGAGAAGCGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9155.35 Da        Isoelectric Point: 3.9951

>AT135570 WP_013573376.1 NZ_CP042357:26363-26611 [Rahnella aquatilis]
MPFEILTSSAASITELKRDPMGTFSAGEGEAVAILNRNEPAFYCVPPDVYAYFLSLAEDVELNRIMDARQGEERIRLTLD
DL

Download         Length: 249 bp

>AT135570 NZ_CP042357:26363-26611 [Rahnella aquatilis]
ATGCCATTTGAAATACTCACTTCCTCAGCTGCAAGTATCACTGAGCTAAAACGTGACCCGATGGGAACGTTTAGCGCAGG
TGAGGGCGAAGCGGTGGCCATCCTTAACCGTAACGAGCCCGCTTTTTATTGTGTTCCACCCGATGTTTACGCCTATTTTC
TGAGTCTTGCAGAAGACGTCGAATTGAACCGCATAATGGATGCGCGGCAGGGTGAAGAAAGGATAAGGCTGACACTGGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBH8NLY8

References