Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1940536..1940807 Replicon chromosome
Accession NZ_CP042352
Organism Escherichia coli strain RM9513

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940574..1940677 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1940536..1940807 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FS836_RS09715 1937693..1939132 + 1440 WP_061344305.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
FS836_RS09720 1939250..1939486 + 237 WP_001295499.1 YebV family protein -
FS836_RS09725 1939591..1939782 + 192 WP_001296140.1 YebW family protein -
FS836_RS09730 1939783..1940439 - 657 WP_000812720.1 protein-serine/threonine phosphatase -
- 1940536..1940807 + 272 - - Antitoxin
- 1940574..1940677 - 104 - - Toxin
FS836_RS09735 1940835..1941176 - 342 WP_000976472.1 YebY family protein -
FS836_RS09740 1941189..1942061 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
FS836_RS09745 1942065..1942439 - 375 WP_000168747.1 CopC domain-containing protein YobA -
FS836_RS09750 1942578..1942808 + 231 WP_000916763.1 DNA polymerase III subunit theta -
FS836_RS09755 1942910..1943566 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
FS836_RS09760 1943590..1944252 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T135524 NZ_CP042352:c1940677-1940574 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT135524 NZ_CP042352:1940536-1940807 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References