Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 6070275..6070778 Replicon chromosome
Accession NZ_CP042331
Organism Bosea sp. F3-2

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag FQV39_RS28260 Protein ID WP_149133323.1
Coordinates 6070584..6070778 (-) Length 65 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag FQV39_RS28255 Protein ID WP_149133322.1
Coordinates 6070275..6070571 (-) Length 99 a.a.

Genomic Context

FQV39_RS28235FQV39_RS28250FQV39_RS28270FQV39_RS28240FQV39_RS28245FQV39_RS28255FQV39_RS28260FQV39_RS28265FQV39_RS28275
Location: 6067172..6067417 (246 bp)
Type: Others
Protein ID: WP_149133318.1
Location: 6069742..6070140 (399 bp)
Type: Others
Protein ID: WP_210251267.1
Location: 6073388..6075037 (1650 bp)
Type: Others
Protein ID: WP_149133325.1
Location: 6067712..6068659 (948 bp)
Type: Others
Protein ID: WP_149133319.1
Location: 6068864..6069619 (756 bp)
Type: Others
Protein ID: WP_149133320.1
Location: 6070275..6070571 (297 bp)
Type: Antitoxin
Protein ID: WP_149133322.1
Location: 6070584..6070778 (195 bp)
Type: Toxin
Protein ID: WP_149133323.1
Location: 6070894..6073272 (2379 bp)
Type: Others
Protein ID: WP_187640095.1
Location: 6075204..6075629 (426 bp)
Type: Others
Protein ID: WP_149134084.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FQV39_RS282356067172..6067417+246WP_149133318.1hypothetical protein-
FQV39_RS282406067712..6068659-948WP_149133319.150S ribosomal protein L11 methyltransferase-
FQV39_RS282456068864..6069619-756WP_149133320.1SDR family oxidoreductase-
FQV39_RS282506069742..6070140+399WP_210251267.1winged helix-turn-helix transcriptional regulator-
FQV39_RS282556070275..6070571-297WP_149133322.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
FQV39_RS282606070584..6070778-195WP_149133323.1type II toxin-antitoxin system HicA family toxinToxin
FQV39_RS282656070894..6073272-2379WP_187640095.1UvrD-helicase domain-containing protein-
FQV39_RS282706073388..6075037+1650WP_149133325.1acyl-CoA dehydrogenase family protein-
FQV39_RS282756075204..6075629-426WP_149134084.1peptide-methionine (R)-S-oxide reductase MsrB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-61)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-78)


Sequences

Toxin        


Download         Length: 65 a.a.        Molecular weight: 7448.69 Da        Isoelectric Point: 10.6659

>T135404 WP_149133323.1 NZ_CP042331:c6070778-6070584 [Bosea sp. F3-2]
MLTNSADIIRRLKREGFVLKSVRGSHQKYVHEATKRMVIVPHPKRDIPIGTVYAIYKDAGWERD

Download         Length: 195 bp

>T135404 NZ_CP042331:c6070778-6070584 [Bosea sp. F3-2]
ATGCTCACCAACAGCGCCGACATCATTCGCCGCCTGAAACGTGAGGGTTTCGTATTGAAAAGCGTGCGCGGCTCTCATCA
GAAATACGTGCATGAGGCAACGAAGCGCATGGTGATCGTCCCCCATCCGAAGCGGGACATTCCAATCGGAACGGTCTATG
CGATATATAAGGATGCGGGCTGGGAACGAGATTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10887.09 Da        Isoelectric Point: 4.0988

>AT135404 WP_149133322.1 NZ_CP042331:c6070571-6070275 [Bosea sp. F3-2]
MRHYIAVVHKDETSCYGVFFPDVKGVFTAGDTLEEAFSQARDALEFAAESWIEDTASDFPEPRSIDELRTDPDFVDASKD
AILMAIPFGRTPARIAAE

Download         Length: 297 bp

>AT135404 NZ_CP042331:c6070571-6070275 [Bosea sp. F3-2]
ATGCGACACTACATTGCAGTCGTCCATAAGGACGAAACATCCTGCTACGGCGTGTTCTTTCCGGACGTGAAGGGGGTGTT
CACGGCCGGCGATACGCTGGAAGAAGCTTTCAGCCAAGCCCGGGACGCCCTCGAGTTTGCAGCGGAAAGCTGGATCGAGG
ATACAGCCTCCGACTTTCCGGAGCCGCGCTCGATCGACGAATTGCGCACCGATCCCGATTTTGTCGACGCCTCCAAGGAC
GCCATCCTGATGGCGATTCCCTTTGGCCGGACACCGGCGCGTATCGCAGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References