Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VapB
Location 5418313..5418911 Replicon chromosome
Accession NZ_CP042331
Organism Bosea sp. F3-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FQV39_RS25055 Protein ID WP_149132759.1
Coordinates 5418313..5418702 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FQV39_RS25060 Protein ID WP_149132760.1
Coordinates 5418699..5418911 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQV39_RS25030 5414035..5414445 + 411 WP_149132754.1 nucleoside diphosphate kinase regulator -
FQV39_RS25035 5414618..5415610 - 993 WP_149132755.1 UDP-glucose 4-epimerase GalE -
FQV39_RS25040 5415782..5416660 + 879 WP_149132756.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
FQV39_RS25045 5416857..5417741 + 885 WP_149132757.1 methyltransferase domain-containing protein -
FQV39_RS25050 5417872..5418309 + 438 WP_149132758.1 acyl-CoA thioesterase -
FQV39_RS25055 5418313..5418702 - 390 WP_149132759.1 PIN domain nuclease Toxin
FQV39_RS25060 5418699..5418911 - 213 WP_149132760.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FQV39_RS25065 5419058..5421268 + 2211 WP_187640061.1 phosphoribosylformylglycinamidine synthase subunit PurL -
FQV39_RS25070 5421280..5421516 + 237 WP_112579526.1 BolA family transcriptional regulator -
FQV39_RS25075 5421563..5421898 + 336 WP_149132761.1 Grx4 family monothiol glutaredoxin -
FQV39_RS25080 5421941..5422189 - 249 WP_149132762.1 DUF1272 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-118)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-48)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14214.49 Da        Isoelectric Point: 6.9680

>T135403 WP_149132759.1 NZ_CP042331:c5418702-5418313 [Bosea sp. F3-2]
VIVVDSSVWIALLRGEASPQVARLRAVENTSDILVGDLVLTEVLQGARDDKHAATIEALMSTFPIVPLLGPSLAPRAAAN
YRRLRQRGITIRKTADVIIATYCIEHGHLLLHQDRDFDPMVEHCGLRTL

Download         Length: 390 bp

>T135403 NZ_CP042331:c5418702-5418313 [Bosea sp. F3-2]
GTGATCGTCGTCGACTCGTCGGTCTGGATCGCTTTGCTGCGCGGCGAGGCCTCGCCCCAAGTCGCGCGGCTCAGGGCTGT
CGAGAATACCTCCGACATCCTGGTCGGCGACCTTGTGCTGACGGAAGTGCTGCAAGGCGCCCGCGACGACAAGCACGCGG
CGACGATCGAAGCGCTGATGTCCACCTTTCCGATCGTGCCGCTACTCGGACCTTCGCTCGCGCCCCGCGCCGCCGCGAAC
TATCGCCGGCTTCGCCAGCGCGGCATCACCATCCGCAAGACAGCCGATGTCATCATCGCCACCTACTGTATCGAGCACGG
CCATCTGCTGCTCCATCAAGACCGCGATTTCGATCCGATGGTGGAGCATTGCGGCCTGCGCACCCTCTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8038.26 Da        Isoelectric Point: 5.8580

>AT135403 WP_149132760.1 NZ_CP042331:c5418911-5418699 [Bosea sp. F3-2]
MRTNIELDDELLAEAMKATGLPTKRATVEEALRLVVRQHRQRRALKELAGLGWEGDLDAMRRDIVLPDER

Download         Length: 213 bp

>AT135403 NZ_CP042331:c5418911-5418699 [Bosea sp. F3-2]
ATGCGCACGAACATCGAACTTGACGACGAATTGCTCGCGGAAGCGATGAAGGCCACGGGGCTGCCGACCAAGCGCGCAAC
GGTCGAGGAAGCGCTGCGGCTCGTCGTTCGGCAGCATCGCCAGCGCCGCGCTCTGAAAGAACTCGCCGGGCTTGGCTGGG
AAGGCGATCTCGACGCGATGCGGCGTGACATCGTCCTGCCTGACGAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References